Current & Future Trends for Big Data in Pharma

1. Big Data in Pharma: Current & Future Trends for Big Data Utilization Across Commercial Function Best Practices, LLC Strategic Benchmarking Research Study with Segmented Responses by Commercial Function www.best-in-class.com

2. Table of Contents • Executive Summary pp. 3-8 • Research Overview pp. 4 • Universe of Learning pp. 5-6 • Big Data Team Overview and Key Study Insights pp. 7-8 • Quantitative Key Findings pp. 9-12 • Defining Big Data pp. 13-20 • Data Types and Sources pp. 21-26 • Data Producers, Dissemination & Requestors pp. 27-31 • Centralization pp. 32-34 • Governance and Leadership pp. 35-51 • About Best Practices, LLC pp. 52

3. Research Project Objectives & Methodology Best Practices, LLC, conducted a customized study – with responses segmented by medical, commercial and HEOR functions - to better understand the growing influence of Big Data in the biopharmaceutical sector and how it impacts medical, HEOR, and commercial operations in the U.S. • Produce reliable industry metrics on current and future trends for Big Data utilization across medical, commercial and HEOR groups. Research Goal Topics Covered • Types of Big Data Projects Used to Support Medical, Commercial and HEOR Decisions • Big Data Capabilities and Governance • Types and Value of Data Used for Big Data Projects • Big Data Staffing and Budget Levels • Value Rating of Partnerships on Big Data Projects • Policies and Procedures Governing Big Data Activities • Investigate data types, data partnerships, and staffing/budget levels companies are using as they move to a more analytically based approach to commercial, HEOR & medical decisions. Research Overview • Best Practices, LLC engaged 12 leaders from 12 pharmaceutical companies through a benchmarking survey. • Research analysts also conducted seven deep-dive executive interviews with selected benchmark participants. Research Methodology

4. Twelve Companies Participated in the Commercial Segment 12 analytics, marketing and HEOR leaders from 12 different companies participated in this study. Participants were recruited because of their presumed investment in Big Data analytics. Benchmark Class:

5. Understanding Big Data Use in Medical, HEOR & Commercial Decision-Making • Big Data Questions • Medical • Commercial • HEOR Analytics Team Big Data Function • Big Data Decisions • Go/No Clinical Decisions • ID Market Opportunities • Developing Economic Models/Assessments • Big Data Info Types • Electronic Health Records • Government Cost Data • Health Outcomes • Big Data Projects • Value Proposition Development • Post-Launch Performance • Real World Studies

6. Quantitative Findings Across the commercial segment, the following key Big Data findings were observed in this study: Only 5 of 36 types of Transactional, Reported, Online, Scientific and Machine-Generated data were rated highly valuable by a majority of study participants. They were: Claims; EHR (Electronic Health Records); Health Outcomes (provider/payer reported); Real World Studies; and Registries. No types of Online or Machine-Generated data were rated highly valuable by a majority of any segment. Forty percent of the study participants said they have a centralized/dedicated Big Data group. Between 30-40% of participants said they expect their data capabilities to increase over the next two years. Only 5 of 36 Types of Data Rated as Highly Valuable Most Have Centralized or Dedicated Big Data Team or Function Small Percent of Participants Expect Data Capabilities to Increase

7. Transactional Data: Commercial Rates Claims, EMR Most Valuable Q: How impactful (or valuable) has each of the following types of transactional data sources proven to be? While a majority of commercial participants rated claims and Electronic Medical Records (EMR) as the most valuable types of transactional data for Big Data studies, 50 % also cited point of sale as highly impactful or valuable. N=12

8. Q: Do you have a centralized/ dedicated group of individuals to support Big Data projects? Commercial Leaders May Face Barriers to Centralized Data Commercial leaders were least likely to describe their analytics as centralized or dedicated. This data point may be driven by discomfort with analysts who address both marketing and clinical questions, something a centralized analytics function might try to do. N=12

9. Q: When do you expect your organization will establish a Big Data team? Commercial Sees Highest Uncertainty On Dedicated Role Commercial leaders were most likely to not know the future structure of their analytics efforts, as well as least likely to have centralized/dedicated personnel already in place. This may be driven by heretofore strict separation of clinical and marketing functions. N=12

10. Q: Please indicate the regions below where your organization has Big Data capabilities, and where Big Data governance resides. Capabilities Outstrip Governance for Commercial Commercial leaders reported marginally more often that there were Big Data capabilities in Asia than other functions. The gap between those with capabilities and those with governance is most pronounced among commercial leaders. N=12

11. About Best Practices, LLC Best Practices, LLC is a research and consulting firm that conducts work based on the simple yet profound principle that organizations can chart a course to superior economic performance by studying the best business practices, operating tactics, and winning strategies of world-class companies. Best Practices, LLC 6350 Quadrangle Drive, Suite 200 Chapel Hill, NC 27517 www.best-in-class.com Download Full Report Download Full Report