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Predictive values. Leena Patel. Sensitivity and Specificity. Measure VALIDITY of test How effective the test is at identifying animals with the disease or without the disease respectively. Predictive value. The probability that the test will give a correct diagnosis
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Predictive values Leena Patel
Sensitivity and Specificity • Measure VALIDITY of test • How effective the test is at identifying animals with the disease or without the disease respectively
Predictive value • The probability that the test will give a correct diagnosis • Positive predictive value (PPV) - a / (a + b) Proportion of pts with a positive test result which really are positive • Negative predictive value(NPV)- d / (c + d) Proportion of pts with a negative test result which really are negativE
Prevalence • PPV and NPV of a test are affected by the prevalence of the disease in the sample population • If high prevalence of disease, then PPV of test is increased and NPV of test is decreased; and vice versa • Predictive values observed in one study do not apply universally
References • www.bmj.com – statistics notes: Diagnostic tests 2: predictive values • Statistics for Veterinary and Animal Science – A. Petrie & P. Watson