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BIO 430: Forensic DNA Analysis

History of DNA typing. 1980 - Ray White describes first polymorphic RFLP marker (Restriction Fragment Length Polymorphism [alleles])1985

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BIO 430: Forensic DNA Analysis

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    1. BIO 430: Forensic DNA Analysis Lecture 2 – History of DNA typing

    3. History of DNA Typing 1986 - RFLP first used in Forensic setting in England to solve a double homicide case 1988 - FBI starts DNA casework 1990 – Human Genome project initiated 1991 – Fluorescent STR markers first described

    4. History of DNA Typing 1992 – FBI starts casework using PCR-based techniques 1993 – First STR kits become available 1994 – O.J. Simpson trial; first publicized case involving DNA evidence

    5. History of DNA Typing 1995 - FSS (Forensic Science Service-UK) starts UK DNA database 1996 – First multiplex STR kits become available 1998 - FBI launches CODIS (Combined DNA Information Service); now FBI use 13 STR loci

    6. History of DNA Typing 2000 – FBI and other labs stop running RFLP cases and convert to multiplex STRs 2003 – Human Genome Project completed (mostly)

    7. Sources of Biological Evidence Blood Semen Saliva Urine Hair Teeth Bone Tissue

    8. Steps in DNA Sample Processing

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