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Classifying the Manifestations of Alzheimer’s Disease in DSM-IV-TR

Classifying the Manifestations of Alzheimer’s Disease in DSM-IV-TR. Eric D. Caine, M.D. John Romano Professor and Chair Departmet of Psychiatry University of Rochester Medical Center Rochester, N.Y. The Expression of Diseases. Fundamental pathobiological processes

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Classifying the Manifestations of Alzheimer’s Disease in DSM-IV-TR

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  1. Classifying the Manifestations of Alzheimer’s Disease in DSM-IV-TR Eric D. Caine, M.D. John Romano Professor and Chair Departmet of Psychiatry University of Rochester Medical Center Rochester, N.Y.

  2. The Expression of Diseases • Fundamental pathobiological processes • molecular • biochemical/physiological • “Primary” manifestations • histopathological • “Secondary” manifestations • clinical signs and symptoms

  3. Huntington’s disease (“chorea”) • CAG repeats • Basal ganglia histopathology/degeneration • Cognitive, psychiatric, motor signs and symptoms

  4. Alzheimer’s disease • Multiple unknown molecular mechanisms • Characteristic histopathology • Cognitive and psychiatric signs and symptoms

  5. Past DSM-IV Classification of Dementia of the Alzheimer’s Type DAT, with early onset 290.10 uncomplicated 290.11 with delirium 290.12 with delusions 290.13 with depressed mood (uncoded specifier: with behavioral disturbance) DAT, with late onset 290.0 uncomplicated 290.3 with delirium 290.20 with delusions 290.21 with depressed mood (uncoded specifier: with behavioral disturbance) Code Alzheimer’s disease (331.0) on Axis III

  6. DSM-IV-TR Coding of Dementia due to Alzheimer’s Disease Dementia due to Alzheimer’s disease 294.10 without behavioral disturbance 294.11 with behavioral disturbance Code Alzheimer’s disease (331.0) on Axis III

  7. DSM-IV Mental Disorders due to Alzheimer’s Disease Psychotic Disorder due to … 293.8 Mood Disorder due to … 293.83 Anxiety Disorder due to … 293.89 Personality Change due to … 310.1 Sleep Disorder due to … 780.5 Code Alzheimer’s disease (331.0) on Axis III

  8. Proposed ICD-10-CM Coding of Dementia due to Alzheimer’s Disease Dementia due to AD, with early onset (G30.0x) G30.00 without behavioral disturbance G30.01 with behavioral disturbance G30.00 unspecified Dementia due to AD, with late onset (G30.1x) G30.10 without behavioral disturbance G30.11 with behavioral disturbance G30.10 unspecified (G codes = ICD-10-CM Diseases of the Nervous System)

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