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Bioinformatics

Explore the field of bioinformatics, a merging of biology and informatics, to analyze genomes, align sequences, design drugs, and study biological databases. Discover the potential for crop and animal stock improvement, pathway analysis, and phylogeny. Learn how bioinformatics and medicine are transforming drug design and genome annotation. Unlock the power of sequence alignment to transfer information between molecules. Explore the vast world of data and databases in bioinformatics. Biologie, Scheikunde, Informatica - Wel leuk! Maar je wilt van alles wat - BIOINFORMATICA!

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Bioinformatics

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  1. Bioinformatics The newest science The integrating science

  2. Bio + informatics

  3. Examples Analysis of the information content of genomes Sequence analysis and sequence alignment Most computational aspects of drug design Data mining in biological databases Model macromolecular structures/complexes Biological pathway analysis Crop and animal stock improvement Phylogeny

  4. The human genome

  5. Chromosomes

  6. ……….the sequence………. ....acccaa gaagtcagaa tcctcgaagc tgaagcctga ctgtaagctc tgcctcctac aactagacaa gtcacaatgc aacccctttg ctccagagga aaaggagtaa gcacagaggg cttctgagtc cggcaatgct ccatttcctg acaggagcat tttacagact tgcgtctgcc cctctgaggg aggcagggcc atcagctaac actcagagac aaggatggtc ctacaacatc ctgatctggg aggaagaggt gaaggcaact caccaccctc aggcatctta acagaaaaca gtggaactaa ggctcattct aaagaatgtg cccaagatca cacaccgaag gctgcaaagc gagagtcaaa cttggaaccc tgaacctgca cttgtccctt tacactgccc tgcagcatgg atgcgatggc tgggcagagg gaagtgccca agcctgggga caaaaatgcc tacctg.... One cubic meter of floppy disks needed to store it all.

  7. Exaggeration competition

  8. Reality (?) The human genome will be known and properly annotated in a few years. At that moment we know nearly all targets for medicines.

  9. Genome annotation

  10. Bioinformaticsand medicine

  11. Drug Design

  12. One genome not enough Parasite Active site

  13. Bioinformaticsand medicine

  14. One genome not enough

  15. Sequences Sequence alignment is the best tool for transferring information from a well studied molecule to a more poorly studied molecule.

  16. Sequences CPISRTWASIFRCW CPISRT---LFRCW CPISRTWASIFRCW CPISRTL---FRCW

  17. Sequences CPISRTEASNFRCW CPISRTQ---FRCW CPISRTEASNFRCW CPISRT---QFRCW

  18. Sequences 1-ASTCIPLKCMMHPICDDERTCASTCF 2-STVLIPIRCMIHPICEEDQVAATTCY 3-ASSCIPPKSMMHPVVDEEKTCASSCF 4-ASTLIPIPVMIHPVVERDKVAAXSCW 5-ASSCIPPPSMMHPIVEEDQVCATTAF 6-ASSCIPIRCMMHPICEEDKVCASSAY 7-ATSLIPPKCMIHPVCDDDRTAASSAT

  19. Data and databases

  20. And now the propaganda Biologie, Scheikunde, Informatica: Wel leuk. Maar je wilt van alles wat.BIOINFORMATICA!!Waar: KUN, Faculteit NWI(In toekomst vermoedelijk op vijf plekken in Nederland).

  21. BIOINFORMATICA overstijgtdisciplines moleculaire levens wetenschappen wiskunde en statistiek medicijnen BIO- INFORMATICA infor-matica scheikunde natuurweten- schappen biologie

  22. Opleidingen scheikunde biologie & medische biologie natuur-wetenschappen informatica en informatie kunde moleculaire levens-wetenschappen life sciences wiskunde natuur- en sterrenkunde milieu- natuur-wetenschappen Faculteit Natuurwetenschappen, Wiskunde en Informatica • 5 subfaculteiten • scheikunde • natuurkunde • biologie • wiskunde • informatica

  23. Studeren aan deze faculteit Basis Orientatie Differentiatie Onderzoek Beroepsvoorbereiding

  24. Vakkenpakketten voor toelating ScheikundeN&T; N&G; WiskB+Nat BiologieN&G; N&T+Biol1&2; Bio+Sk NatuurwetenschappenN&T; N&G+WiskB2; Nat+WiskB InformaticaN&T; N&G+WiskB2; WiskB Moleculaire LevenswetenschappenN&T; N&G; WiskB+Nat

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