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Bioinformatics

Bioinformatics. The application of computer technology to the management of biological information. http://www.bioplanet.com/whatis.html http://en.wikipedia.org/wiki/Bioinformatics http://www.ebi.ac.uk/2can/bioinformatics/. Background. 1978 Paulien Hogeweg

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Bioinformatics

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  1. Bioinformatics The application of computer technology to the management of biological information http://www.bioplanet.com/whatis.html http://en.wikipedia.org/wiki/Bioinformatics http://www.ebi.ac.uk/2can/bioinformatics/

  2. Background • 1978 PaulienHogeweg • the study of information processes in biotic systems • Evolved so much that the most pressing task now involves the analysis and interpretation of various types of data • Primary goal = to increase the understanding of biological processes http://www.bioplanet.com/whatis.html http://en.wikipedia.org/wiki/Bioinformatics

  3. Major Research Areas • Sequence analysis • Shotgun sequencing • Genome annotation • Computational evolutionary biology • Literature analysis • Analysis of gene expression • Analysis of regulation http://en.wikipedia.org/wiki/Bioinformatics

  4. Major Research Areas • Analysis of protein expression • Analysis of mutations in cancer • Comparative genomics • Modeling biological systems • High-throughput image analysis • Structural bioinformatic approaches • Prediction of protein structure • Molecular interaction http://en.wikipedia.org/wiki/Bioinformatics

  5. Applications • Molecular medicine • More drug targets • Personalized medicine • Preventative medicine • Gene therapy http://www.ebi.ac.uk/2can/bioinformatics/bioinf_realworld_1.html

  6. Applications • Microbial genome applications • Waste cleanup • Climate change • Alternative energy sources • Biotechnology • Antibiotic resistance • Forensic analysis of microbes • Bioweapon creation • Evolutionary studies http://www.ebi.ac.uk/2can/bioinformatics/bioinf_realworld_1.html

  7. Applications • Agriculture • Crops • Insect resistance • Imporve nutritional quality • Crops in poor soil and that are drought resistant • Animals • Comparative studies http://www.ebi.ac.uk/2can/bioinformatics/bioinf_realworld_1.html

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