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One Health Initiative Global Clearinghouse for Action involving Rabies and Other Zoonoses. the pro bono OHI Team Laura Kahn MD Bruce Kaplan DVM Tom Monath MD Jack Woodall PhD. Definition.
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One Health InitiativeGlobal Clearinghouse for Action involving Rabies and Other Zoonoses thepro bonoOHI Team Laura Kahn MD Bruce Kaplan DVM Tom Monath MD Jack Woodall PhD
Definition “One Health is the collaborative efforts of multiple disciplines working locally, nationally, and globally to attain optimal health for People & other animals, plantsand our environment.”
Rabies: PerfectExampleofhowOneHealthis essential • Physiciansto vaccinate & treatvictims • Veterinariansto vaccinate & sterilizedogs & cats • Wildlifeexpertsto adviseon oral vaccination • Ecologiststo tellresponsibleauthoritieswhy sterilization is betterthanculling • Sanitarians to eliminategarbagethatfeedsstrays • Educatorsto teachpeople to vaccinatetheir pets • Mediato informaboutrisks & prevention, e.g. bats
Benefit - Synergism The One Health concept is a worldwide strategy for expanding • interdisciplinarycollaboration & communication • in all aspects of health care for • humans, animals and the environment. The synergism achieved will advance health care for the 21st century & beyond by…
1. Accelerating biomedical research discoveries Multidisciplinary teams of veterinarians, physicians, virologists & wildlife ecologists were responsible for: • Development of cell culture and oral-bait wildlife rabiesvaccines • Discovery oftheLyassavirus family ofrabies-relatedviruses • Developing PCR methods for detection ofrabies • Human monoclonal antibodies for post-exposuretreatment for rabies
Accelerating biomedical research discoveries (cont.) More examples: • Cancer (human & animal) • breast, ovaries, liver, skin melanoma vaccines • Orthopedic diseases/devices (human & animal) • treat human osteoarthritis, develop prostheses, artificial joints • Heartdisease(human) • treat and prevent heart attacks with intra-coronary arterial “stents”, new drugs
2. Enhancing public health efficacy Examples: • Multidisciplinary collaborations of physicians, veterinarians, nurses, microbiologists, engineers, sanitarians, dentists, statisticians, entomologists, ecologists and others • Collaborations between local, state, and national agencies – (including local local & state state) – to facilitate and advance disease prevention & control
3. Expeditiously expanding the scientific knowledge base Historicexamples: • Discovery and naming Ebola virus • K.M. Johnson MD, F. A. Murphy DVM & others at CDC (USA), 1976. • Nobel prize for physiology or medicine • collaborative research by immunologists R. M. ZinkernagelMD & P.C. Doherty DVM uncovers basic science of how body distinguishes normal from virus-infected cells, 1996.
Expeditiously expanding the scientific knowledge base (cont.) Current examples: • Surveillance for bat Lyssaviruses and disease • Quantitating rabies exposure health risks • Defining transmission dynamics and molecular epidemiology of rabies strains • Improving rabies vaccination techniques, e.g. intradermal inoculation
4. Improving medical education and clinical care • Significant, improved patient education if physicians and veterinarians advise patients/clients collaboratively about zoonotic risks from pets and wildlife. • Knowledge sharing (comparative medicine) at schools of medicine and veterinary medicine – learning how animal and human health impact each other.
OneHealthInitiativewww.onehealthinitiative.com Global Clearinghouse for One Health Action • News items - current & upcoming events • WORLD RABIES DAY, College One Health clubs, national and international One Health meetings • Publications – relevant to One Health studies • One Health Newsletter quarterly (Florida Dept. of Health) • ProMED-mail.orgOne Health outbreak reports • Twitter – One Healthitems
OneHealth Initiative.com • 23 Endorsing Institutions, including: • American Medical Association (AMA) • American Veterinary Medical Association (AVMA) • American Society for Tropical Medicine and Hygiene (ASTMH) • U.S. Centers for Disease Control & Prevention (CDC) • U.S. Department of Agriculture (USDA) • U.S. National Environmental Health Association (NEHA)
OneHealthInitiativewww.onehealthinitiative.com Overseas Institutions, including: • Colombia:Corporación Red SPVet • Croatia: Society for Infectious Diseases • India: Veterinary Public Health Association • Italy: Society of Preventive Medicine • Netherlands:Immuno Valley Consortium
OneHealthInitiativewww.onehealthinitiative.com Joinmore than 500 prominent scientists, physicians, veterinarians & environmentalists worldwide who have endorsed the initiative
www.onehealthinitiative.com One Health implementation will help protect and/or save untold millions of lives in our generation and for those to come www.onehealthinitiative.com