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Case 3. Basic clinical data. 51-year-old Caucassian male Tumor of the kidney 17 x 16 x 12 cm Widely necrotic (80% of tumorous mass) Vital part was grey with hemorrhagias on cut section. ???. Locust vs. Trixalis or Acrida. Positive reactions AE1-AE3 EMA Vimentin. Negative reactions
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Basic clinical data • 51-year-old Caucassian male • Tumor of the kidney 17 x 16 x 12 cm • Widely necrotic (80% of tumorous mass) • Vital part was grey with hemorrhagias on cut section
Positive reactions AE1-AE3 EMA Vimentin Negative reactions HMB45 S-100 CAM 5.2 Actin S Immunohistochemistry
Synonyms • Loopoma • RCC with lower-nephron differentiation • Low grade collecting duct RCC • Spindle and cuboidal RCC • Low grade spindle cell RCC
Mucinous tubular and spindle cell carcinoma • Age range 17-82 years • Females are affected more frequently • Usually disclosed by ultrasonographic examination for different reasons • Favourable prognosis- low-grade tumors • Only 2 metastatic cases in the world literature
Mucinous tubular and spindle cell carcinoma • Differential diagnostics: Papillary RCC Sarcomatoid RCC Angiomyolipoma Metastasis of adenocarcinoma