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The CTSAs and NCRR’s vision for a National Consortium

The CTSAs and NCRR’s vision for a National Consortium. Dr. Anthony R. Hayward Director DCRR/NCRR. Assembling resources for clinical researchers. community engagement. animal model resources. science education. Pre-clinical. mouse. Improved patient care. Community.

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The CTSAs and NCRR’s vision for a National Consortium

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  1. The CTSAs and NCRR’s vision for a National Consortium Dr. Anthony R. Hayward Director DCRR/NCRR

  2. Assembling resources for clinical researchers community engagement animal model resources science education Pre-clinical mouse Improved patient care Community research capacity & training MRI insertiontube imaging & informatics advances Clinical clinical research support NCRR

  3. WA ME MT ND VT OR MN NH WI ID SD NY MA MI WY RI PA IA NE NV OH MD IN DE IL UT CO WV KS VA CA MO KY NC TN OK AR AZ SC NM GA AL MS AK TX LA FL HI Building a National CTSA Consortium(46 CTSA sites in 26 states; 60 sites when fully implemented) NJ = IDeA-Eligible States PR = CTSA State = IDeA-Eligible State and CTSA Member

  4. CTSA philosophy • Serve NIH funded clinical investigators • Increase the efficiency of clinical and translational research • Integrate translational and clinical science by fostering collaboration between the departments and schools of an institution and between institutions and industry • Share and lead as a consortium

  5. Progress • Awards in 2010 and 2011 will extend consortium to 60 CTSAs • We have a broad spectrum of activity: child health, community, dentistry, aging, drug development • Strategic Goals defined and refined • Challenges: • Communications • Efficient sharing of resources • Outreach to non-CTSA sites

  6. Outreach to fill the gaps • In the local environment • Within and outside the awardee institution. • At a regional level • Leveraging opportunities: COBRE and INBRE • Self assembly of regional networks • At a consortial level • Flexible governance structure

  7. Sharing of data: common vocabulary • Indiana CTSI will enhance interoperability within and among clinical care and research systems by (1) extending the LOINC coding system to incorporate the high priority Measures for the research Domains contained in the Phenotypes and eXposures (PhenX) toolkit; (2) extend the LOINC coding system to incorporate the variables in the Patient-reported Outcomes Measurement Instrument System (PROMIS) Item Bank; (3) extending the LOINC coding system to incorporate other prioritized clinical research tests, measures, and assessment instruments; and (4) disseminating the standardized clinical research content within the main LOINC distribution free of charge worldwide.

  8. Responding to investigators’ needs • Access to clinical research tools • Access to career development opportunities • Priorities shared with consortium • Improved clinical research management • Speedier location of resources • Faster human subject accrual • Help with regulatory requirements • Benefits from speaking with a common voice

  9. Implementing the vision: CTSA projects listed by Strategic Goal Topics Calculations based on % of 165 total projects. Total % exceeds 100% because some projects are aligned to more than one topic.

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