Artificial Organs Market Trends, Industry and Analysis

1. Global Artificial Organs Market Focus on Organ Type, Technology Type, Competitive Landscape, Pipeline Products Data, and 12 Countries Data - Analysis and Forecast: 2018-2023 Key Questions Answered in the Report ƒ What are the artificial organs’ key features which make them a suitable sub- stitute to organ transplants? What are the advantages of artificial organs over conventional organ trans- plants? How did the artificial organs market evolve, and what is its scope in the future? What are the major market drivers, challenges, and opportunities in the glob- al artificial organs market? What are the key developmental strategies which are implemented by the key players to stand out in this market? What are the leading companies dominating the global artificial organs mar- ket? How many types of artificial organs are available in the market, and which are the companies offering the artificial organs? Based on organ type, which artificial organ type is anticipated to witness massive rise in the demand in the forecast period and in which region? What are the different implantable and wearable artificial organs available in the market? Which technology between the two is leading and why? What are investors’ perceptions about the global artificial organs market? Also, what is the funding scenario of the market? What are the key companies which made substantial investments to aid technological advancements in the market? What are the regulations pertaining to the global artificial organs market? What are initiatives implemented by different government bodies to combat the shortage of organ crisis? What was the market value of the leading segments and sub-segments of the global artificial organs market? How will each segment of the global artificial organs market grow during the forecast period, and what will be the revenue generated by each of the segments by the end of 2023? How will the industry evolve during the forecast period 2018-2023? Which region will contribute to the highest sales of the global artificial organs market during the forecast period? Which region carries the potential for the significant expansion of key compa- nies for different artificial organ types? ƒ ƒ MORE THAN 80 COMPANIES RESEARCHED ƒ ƒ ACROSS THE VALUE ƒ CHAIN ƒ ƒ METICULOUS COMPILATION OF MORE THAN 700 RESEARCH HOURS ƒ ƒ ƒ EXCLUSIVE INSIGHTS ƒ FROM IN-DEPTH EXPERT INTERVIEWS ƒ ƒ CONTAINS 22 MARKET DATA TABLES AND 156 FIGURES SPREAD ACROSS 255 PAGES ƒ ƒ ƒ sales@bisresearch.com | www.bisresearch.com

2. Table of Contents MARKET OVERVIEW COMPANY PROFILES ƒ Introduction ƒ Transplantation and Rising Need for Artificial Organs ƒ The Widening Gap between Demand and Supply of Organs ƒ Advent of Artificial Organs and Current Status ƒ Impact of Artificial Organs: Advantages and Disadvantages ƒ The Future of Artificial Organs ƒ Global Market Scenario ƒ Assumptions and Limitations ƒ Overview ƒ Advanced Bionics AG and affiliates ƒ Boston Scientific Corporation ƒ CARMAT ƒ Cochlear Ltd. MARKET DYNAMICS ƒ Dexcom, Inc. ƒ Insulet Corporation ƒ Overview ƒ Impact Analysis ƒ Market Drivers ƒ Challenges ƒ Opportunities ƒ KeraMed, Inc. ƒ MED-EL ƒ Medtronic plc ƒ Oticon Medical COMPETITIVE LANDSCAPE ƒ PIXIUM VISION ƒ Key Developments and Strategies ƒ Industry Attractiveness ƒ Retina Implant AG ƒ Second Sight Medical Products, Inc. REGULATORY FRAMEWORK ƒ SynCardia Systems, LLC ƒ Legal Requirements and Framework at International Level ƒ Legal Requirements and Framework in the Americas ƒ Legal Requirements and Framework in Europe ƒ Legal Requirements and Framework in Asia-Pacific ƒ Tandem Diabetes Care, Inc. RESEARCH SCOPE AND METHODOLOGY GLOBAL ARTIFICIAL ORGANS MARKET (BY ORGAN TYPE) ƒ Report Scope ƒ Overview ƒ Artificial Pancreas ƒ Artificial Heart ƒ Artificial Ear ƒ Artificial Eye ƒ Artificial Urinary Bladder ƒ Global Artificial Organs Market: Research Methodology GLOBAL ARTIFICIAL ORGANS MARKET (BY TECHNOLOGY) ƒ Overview ƒ Wearable Technologies ƒ Implantable Technologies GLOBAL ARTIFICIAL ORGANS MARKET (BY REGION) ƒ Global Artificial Organs Market: Analysis of Growth Potential of Different Countries ƒ Global Overview ƒ North America ƒ Europe ƒ Asia-Pacific ƒ Rest-of-the-World VIEW COMPLETE TABLE OF CONTENT sales@bisresearch.com | www.bisresearch.com

3. List of Tables 1. Global Artificial Organs Market, 2017 and 2023 2. Total Number of Donors in Different Countries in 2015 [Data presented in absolute number and rate per million inhabitants (pmp)] 3. Total Number of Organ Transplantation (Tx) in Different Countries in 2015 [Data presented in absolute number and rate per million inhabitants (pmp)] 4. Impact Analysis of Market Drivers 5. Impact Analysis of Market Challenges 6. Percentage of Total Regional Population Aged 65 Years & Above: 2015 & 2030 7. Contribution of Risk Factors to Lifestyle Diseases (Percentage of Individual Population Attributable Fraction) 8. Disease Burden Due to Common Lifestyle Diseases across Different Regions, 2016 9. Funding Initiatives by Government and Research institutes 10. Funding Initiatives by Private and Public Companies 11. Research and Development Expenses in 2016 and 2017 ($Million) 12. Post-Operational Consequences of SynCardia TAH Implantation 13. Post-Operational Consequences of Total Artificial Heart (TAH) Implantation 14. Regulatory Authorities/Associations/Consortiums for Medical Devices in the Americas 15. Regulatory Authorities/Associations/Consortiums for Medical Devices in Europe 16. Regulatory authorities/associations/consortiums for Medical Devices in Asia-Pacific 17. Pipeline Products of Artificial Pancreas 18. List of Companies and Product Offerings in Artificial Organs Market (by Ear) 19. List of Companies and Product Offerings in Artificial Organs Market (by Eye) 20. Pipeline Products of Artificial Eye 21. List of Artificial Organs with Wearable Technologies 22. List of Artificial Organs with Implantable Technologies sales@bisresearch.com | www.bisresearch.com

4. List of Figures 1. 2. 3. Types of Artificial Organs Global Artificial Organs Market Snapshot Impact of Market Drivers and Market Restraints, 2017 Share of Key Developments and Strategies, January 2014-August 2018 Market Share of Key Companies, 2016 and 2017 Global Artificial Organs Market Share (by Organ Type), 2017-2023 Global Artificial Organs Market Share (by Organ Type), 2017-2023 Global Artificial Organs Market Share (by Region), 2017 and 2023 Factors Playing Significant Role in Demand and Supply of Organs Evolution of Artificial Organs Advantages and Disadvantages of Artificial Organs Global Artificial Organs Market, 2017-2023 Market Dynamics Projected Global Geriatric Population Aged 60 Years and Above (Billion), 1900-2100 Number of Donors Recovered and Patients Waiting at the Year-end vs. Number of Transplants Performed, 2010-2017 Function of Multi Organs-on-Chips Competitive Landscape (January 2010-October 2018) Share of Key Developments and Strategies, January 2014-August 2018 Product Approvals (by Company), January 2010-August 2018 Agreements, Collaborations, and Partnerships (by Company), January 2010-August 2018 Funding Activities (by Company), January 2010-August 2018 Product Launches and Developments (by Company), January 2010-August 2018 Acquisitions (by Company), January 2010-August 2018 Market Share Analysis for Global Artificial Organs Market, 2016 Market Share Analysis for Global Artificial Organs Market, 2017 Growth Share Matrix for Global Artificial Organs Market (by Organ Type), 2017 Bargaining Power of Suppliers: Overall Impact Bargaining Power of Buyers: Overall Impact Threat of New Entrants: Overall Impact 30. 31. 32. Threat of Substitute Products: Overall Impact Intensity of Competitive Rivalry: Overall Impact Artificial Organs Market Segmentation (by Organ Type) Global Artificial Organs Market (by Organ Type), 2017-2023 Mechanism of Action of Artificial Pancreas Global Artificial Organs Market (by Pancreas), 2017- 2023 Revenue Forecast of Companies with Artificial Pancreas in Pipeline, 2019-2023 Mechanism of Action of TAH Key Points about AbioCor Global Artificial Organs Market (by Heart), 2017- 2023 Sales of SynCardia System, LLC’s TAH (by Volume), 2009-2023 Mechanism of Action of Cochlear Implants Global Artificial Organs Market (by Ear), 2017-2023 Mechanism of Action of Artificial Retina Global Artificial Organs Market (by Eye), 2017-2023 Key Points on AMS 800 Urinary Control System Global Artificial Organs Market (by Urinary Bladder), 2017-2023 Artificial Organs Market Segmentation (by Technology) Global Artificial Organs Market (by Technology), 2017-2023 Global Artificial Organs Market (by Wearable Technologies), 2017-2023 Global Wearable Artificial Organs Market (by Organ Types), 2017-2023 Global Artificial Organs Market (by Implantable Technologies), 2017-2023 Global Implantable Artificial Organs Market (by Organ Type), 2017-2023 Contribution of Different Artificial Organs in Different Geographical Regions, 2017 Artificial Pancreas: Analysis of Potential Growth Factors Across Different Regions Artificial Heart: Analysis of Potential Growth Factors across Different Regions Artificial Eye and Artificial Ear: Analysis of Potential Growth Factors across Different Regions Global Artificial Organs Market (by Region), 2017 and 2023 North America: Artificial Organs Market, 2017-2023 North America: Market Dynamics 4. 33. 5. 6. 34. 35. 7. 36. 8. 37. 38. 39. 9. 10. 11. 12. 13. 14. 40. 41. 42. 43. 44. 45. 46. 15. 16. 17. 47. 48. 18. 49. 19. 50. 20. 51. 21. 52. 22. 53. 23. 54. 24. 55. 25. 56. 26. 57. 27. 28. 29. 58. 59. sales@bisresearch.com | www.bisresearch.com

5. List of Figures 60. North America: Artificial Organs Market (by Country), 2017-2023 Number of Donors Recovered and Transplants Performed per Year vs. Patients Waiting at Year End The U.S.: Artificial Organs Market, 2017-2023 Canada: Artificial Organs Market, 2017-2023 Europe: Artificial Organs Market, 2017-2023 Europe: Market Dynamics Europe: Artificial Organs Market (by Country), 2017- 2023 Germany: Artificial Organs Market, 2017-2023 The U.K.: Artificial Organs Market, 2017-2023 France: Artificial Organs Market, 2017-2023 Number of Patients on an Organ Donation Waiting List in Italy in 2017 Italy: Artificial Organs Market, 2017-2023 Sweden: Artificial Organs Market, 2017-2023 Rest-of-Europe: Artificial Organs Market, 2017-2023 Asia-Pacific: Artificial Organs Market, 2017-2023 Asia-Pacific: Market Dynamics Asia-Pacific: Artificial Organs Market (by Country), 2017-2023 Japan: Artificial Organs Market, 2017-2023 China: Artificial Organs Market, 2017-2023 Australia: Artificial Organs Market, 2017-2023 India: Artificial Organs Market, 2017-2023 Singapore: Artificial Organs Market, 2017-2023 Rest of Asia-Pacific: Artificial Organs Market, 2017- 2023 Rest-of-the-World: Artificial Organs Market, 2017- 2023 Rest-of-the-World: Market Dynamics Rest-of-the-World: Artificial Organs Market (by Region), 2017-2023 Latin-America: Artificial Organs Market, 2017-2023 Middle-East and Africa: Artificial Organs Market, 2017-2023 Shares of Key Company Profiles Advanced Bionics AG and affiliates Product Portfolio for Artificial Organs Market Advanced Bionics AG and affiliates: SWOT Analysis Boston Scientific Corporation: Product Portfolio for Artificial Organs Market Boston Scientific Corporation: Overall Financials, 2015-2017 Boston Scientific Corporation: Revenue (by Segment), 2015-2017 Boston Scientific Corporation: Revenue (by Region), 2015-2017 Boston Scientific Corporation: R&D Expenditure (2015-2017) Boston Scientific Corporation: Revenue Forecast, 2014-2020 Boston Scientific Corporation: SWOT Analysis CARMAT Product Portfolio for Artificial Organs Market CARMAT: SWOT Analysis 100. Cochlear Ltd.: Product Portfolio for Artificial Organs Market 101. Cochlear Ltd.: Overall Financials, 2016-2018 102. Cochlear Ltd.: Revenue (by Segment), 2016-2018 103. Cochlear Ltd.: Revenue (by Region), 2016-2018 104. Cochlear Ltd.: R&D Expenditure 105. Cochlear Ltd.: Revenue Forecast, 2015-2020 106. Cochlear Ltd.: SWOT Analysis 107. Dexcom, Inc.: Product Portfolio for Artificial Organs Market 108. Dexcom, Inc.: Overall Financials, 2015-2017 109. Dexcom, Inc.: Revenue (by Region), 2015-2017 110. Dexcom, Inc.: R&D Expenditure (2015-2017) 111. Dexcom, Inc.: Revenue Forecast, 2014-2020 112. Dexcom, Inc.: SWOT Analysis 113. Insulet Corporation: Product Portfolio for Artificial Organs Market 114. Insulet Corporation: Overall Financials, 2015-2017 115. Insulet Corporation: Revenue (by Region), 2015- 2017 116. Insulet Corporation: R&D Expenditure (2015-2017) 117. Insulet Corporation: Revenue Forecast, 2014-2020 118. Insulet Corporation: SWOT Analysis 119. KeraMed, Inc. Product Portfolio for Artificial Organs Market 120. KeraMed, Inc.: SWOT Analysis 121. MED-EL Product Portfolio for Artificial Organs Market 122. MED-EL: SWOT Analysis 123. Medtronic plc: Product Portfolio for Artificial Organs Market 124. Medtronic plc: Overall Financials, 2016-2018 125. Medtronic plc: Revenue (by Segment), 2016-2018 126. Medtronic plc: Revenue (by Region), 2016-2018 127. Medtronic plc: R&D Expenditure 128. Medtronic plc: Revenue Forecast, 2015-2020 129. Medtronic plc: SWOT Analysis 94. 61. 95. 62. 63. 64. 65. 66. 96. 97. 98. 99. 67. 68. 69. 70. 71. 72. 73. 74. 75. 76. 77. 78. 79. 80. 81. 82. 83. 84. 85. 86. 87. 88. 89. 90. 91. 92. 93. sales@bisresearch.com | www.bisresearch.com

6. List of Figures 130. Oticon Medical Product Portfolio for Artificial Organs Market 131. Oticon Medical: SWOT Analysis 132. PIXIUM VISION Product Portfolio for Artificial Organs Market 133. PIXIUM VISION: SWOT Analysis 134. Retina Implant AG Product Portfolio for Artificial Organs Market 135. Retina Implant AG: SWOT Analysis 136. Second Sight Medical Products, Inc.: Product Portfolio for Artificial Organs Market 137. Second Sight Medical Products, Inc.: Overall Financials, 2016-2018 138. Second Sight Medical Products, Inc.: Revenue (by Region), 2016-2018 139. Second Sight Medical Products, Inc.: R&D Expenditure 140. Second Sight Medical Products, Inc.: SWOT Analysis 141. SynCardia Systems, LLC Product Portfolio for Artificial Organs Market 142. SynCardia Systems, LLC: SWOT Analysis 143. Tandem Diabetes Care, Inc. Product Portfolio for Artificial Organs Market 144. Tandem Diabetes Care, Inc.: Overall Financials, 2015-2017 145. Tandem Diabetes Care, Inc.: R&D Expenditure (2015-2017) 146. Tandem Diabetes Care, Inc.: Revenue Forecast, 2014-2020 147. Tandem Diabetes Care, Inc.: SWOT Analysis 148. Global Artificial Organs Market Segmentation 149. Global Artificial Organs Market Research Methodology 150. Primary Research 151. Secondary Research 152. Data Triangulation 153. Bottom-up Approach (Segment-wise Analysis) 154. Top-down Approach (Segment-wise Analysis) 155. Assumptions and Limitations 156. Considered Factors for Data Prediction and Modelling sales@bisresearch.com | www.bisresearch.com

7. Research Scope & BIS Methodology 1. Scope of the Report The report constitutes of an in-depth study of the global artificial organs market, including a thorough analysis of the types of products. The study also presents a detailed analysis of the market dynamics and the estimation of the market size over the forecast period 2018-2023. The scope of this report is focused on the artificial organ products for different applications and their country-wise analysis. The report does not take into consideration any product related to tissue engineering. The scope of the artificial organs market was formulated to only include medical devices which function as organs. The market analysis includes an in-depth examination of the key ecosystem players and key strategies and developments taking place in this market. Further, it includes the market dynamics (market drivers, opportunities, and challenges) and industry analysis. The purpose of the study is to gain a holistic view of the global artificial organs market in terms of various factors influencing the market, including regulatory reforms and technological advancements. The market has been segmented into ‘organ type’, ‘technology’, and ‘regions’. The scope of this report is centered upon conducting a detailed study of the products allied with the artificial organs market. The report also comprises an opportunity analysis of different artificial organs for different indications in North America, Europe, Asia-Pacific, Latin America, and Rest-of- the-World regions. Moreover, the study also includes the exhaustive information on the unmet needs, perception on the new products, competitive landscape (including pipeline analysis), market share of leading manufacturers, growth potential of each product, application, and region, as well as other vital information with respect to the global artificial organs market. Products for which no real-time data was available in the public domain, personnel from the respective companies were contacted in order to gain valuable information pertaining to the product in different regions and their corresponding prices. This information was then used to estimate the global number for a particular product which was later validated by the industry experts. 2. BIS Research Market Research Methodology The research methodology design adopted for this specific study includes a mix of data collected from primary and secondary sources. Both primary sources (in-house experts, industry leaders, and market players) and secondary sources (a host of paid and unpaid databases) along with analytical tools have been used exhaustively to build the forecast and predictive models. sales@bisresearch.com | www.bisresearch.com

8. Research Scope & BIS Methodology Figure 1: Research Methodology Scope Definition Research Design Market Study Qualitative Quantitative Primary Interviews/ Secondary Research Top Down and Bottom Up Primary & Secondary Data Report Writing Data Validation Data Analysis Data Collection Primary Data Sources ƒ The key data points taken from the primary sources include: ƒ Validation and triangulation of all the numbers and graphs ƒ Validation of report segmentation and key qualitative findings ƒ Understanding the competitive landscape ƒ Understanding and considering the factors for market dynamics of various market segments and sub- segments ƒ Validation of impact analysis of macro and micro factors in different countries ƒ Percentage split of individual markets for geographical analysis sales@bisresearch.com | www.bisresearch.com

9. Research Scope & BIS Methodology Figure 2: Secondary Data Sources The research study involves the usage of extensive secondary sources such as databases, company websites, and annual reports, among others. The following figure exhibits key secondary data sources considered in this report: Stock Analyst Websites Company Sources ƒ ƒ ƒ ƒ Seeking Alpha Yahoo Finance Wiki Finance The Wall Street Journal ƒ ƒ ƒ ƒ ƒ Annual Reports Press Releases Sec Filings Investor Presentations Financial Disclosures SECONDARY DATA SOURCES Government and Regulatory Sources Public and Private Database ƒ Centers for Disease Control and Prevention (CDC) The World Health Organization (WHO) The National Health Services (NHS) The National Center for Biotechnology Infromation (NCBI) The Food & Drug Administration of United States (U.S. FDA) ƒ ƒ ƒ ƒ ƒ ƒ ƒ Medline PubMed National Library of Medicine ProQuest CMS Database Medicare Beneficiary Database Oxon Epidemiology ƒ ƒ ƒ ƒ The key data points taken from the secondary sources include: ƒ Segmentation breakups, split-ups, and percentage shares ƒ Data for market value ƒ Key industry trends of the top players of the market ƒ Qualitative insights into various aspects of the market, key trends, and emerging areas of innovation ƒ Quantitative data for mathematical and statistical calculations sales@bisresearch.com | www.bisresearch.com

10. Research Scope & BIS Methodology Figure 4: Data Triangulation The following figure exhibits data triangulation considered: BIS Research Internal Repository ƒ ƒ ƒ ƒ ƒ ƒ ƒ ƒ Key Players Competitive Landscape Opportunities/Challenges Market Size and Market Share Influencing Factors Market estimates Geographical Analysis Market Trends Bis Research Internal Repository DATA TRIANGULATION Primary Sources Secondary Sources Primary Sources Secondary Sources Supply Side ƒ Annual reports from the leading players in the artificial organs market National Centre of Biotechnology Information The World Bank Interview With: ƒ ƒ ƒ Top management of leading medical device companies developing artificial organs C-level executives of start-up companies innovating in the medical device field Scientists and researchers from renowned universities working on artificial organs ƒ Annual Reports, SEC Filings, Investor Presentations, Websites, and Press Releases of top players, News Articles, Journals, and Paid Databases ƒ REQUEST FOR SAMPLE sales@bisresearch.com | www.bisresearch.com

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