1 / 20

Gaussian Chain Entropy only. Infinite extensibility.

Gaussian Chain Entropy only. Infinite extensibility. 2. Freely Jointed Chain. Entropy. Finite extensibility. Rigid rods. . 3. Wormlike Chain. Entropy. Finite extensibility. Bending elasticity. Smooth curve like cooked spaghetti. Persistence length .  = 50nm.

bodner
Download Presentation

Gaussian Chain Entropy only. Infinite extensibility.

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Gaussian Chain • Entropy only. • Infinite extensibility. 2. Freely Jointed Chain. Entropy. Finite extensibility. Rigid rods.  3. Wormlike Chain. Entropy. Finite extensibility. Bending elasticity. Smooth curve like cooked spaghetti.

  2. Persistence length   = 50nm  = 6mm = bigger than a cell  = 17m

  3. Mechanism of DNA virus assembly and DNA packaging Rao and Feiss – Annu Rev Virol (2015) 2(1): 351–378 Costs of DNA packaging: DNA bending + Electrostatic repulsion of charged DNA + Entropic cost of confinement

  4. Measuring the force generated by T4 DNA packaging motors Fuller et al PNAS (2007) 104: 16868-16873 Tension in the DNA increases as packaging proceeds. Eventually the tether breaks. Speed of motpor decreases as tension increases.

  5. Differential Scanning Calorimetry of Bacteriophage . Exothermic peaks associated with Capsid denaturation and DNA melting. Endothermic peak due to DNA ejection. Shows that there was significant stored energy in the packaged DNA Bauer et al J Virol (2015) 89:9288-9298

  6. Kunze and Netz (2000)

  7. Brower-Toland et al 2002

  8. Mihardja et al (2006)

  9. Kulic and Schiessel 2004

  10. Tomschik et al 2005

More Related