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NLE1b - 8 -22b (I)

1. 19.1 19.2::1.2 1.4. Pericentric inversion. NLE1b - 8 -22b (I). 11.1 11.2 11.5 11.6. 11.1 11.2::11.9 11.7. 11.7 11.9 11.10. 11.6 11.5 11.2::11.9 11.10. 11. 1.5 1.8. 1. 11. 1.1 1.2 1.4. HyA11. HyA11(inv). 19.1 19.2 19.3. reciprocal translocation. 19.4 19.5

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NLE1b - 8 -22b (I)

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  1. 1 19.1 19.2::1.2 1.4 Pericentric inversion NLE1b - 8 -22b (I) 11.1 11.2 11.5 11.6 11.1 11.2::11.9 11.7 11.7 11.9 11.10 11.6 11.5 11.2::11.9 11.10 11 1.5 1.8 1 11 1.1 1.2 1.4 HyA11 HyA11(inv) 19.1 19.2 19.3 reciprocal translocation 19.4 19.5 19.6 19.7 19 HyA19 T1(1/19) resumed in NLE11&17 1.5 1.8 Pericentric inversion 13.1 13.2 13.3 13.1 13.2::13.5 13.4 13.4 13.5 13.6 1.1 1.2::19.2 19.3 13 13.3 13.2::13.5 13.6 19.4 19.5 19.6 19.7 19 13 HyA13 HyA1 see next slide NLE22a T2(19/1) resumed in the next slide

  2. 11.1 11.2::11.9 11.7 11.6 11.5::19.6 19.5::13.4 13.5::13.2 13.1 NLE1b - 8 -22b (II) reciprocal translocation reciprocal translocation 11.1 11.2::11.9 11.7 13.1 13.2::13.5 13.4 11 11.1 11.2::11.9 11.7 T2(19/1) intermediate previous slide 11.6 11.5::19.6 19.5 19.4 19.3 19.2::1.2 1.1 13.3 13.2::13.5 13.6 19 11.6 11.5 11.2::11.9 11.10 1.1 1.2::19.2 19.3 NLE1b 13 19.4 19.5 19.6 19.7 11 11 19 NLE22a 1 NLE1A HyA11(inv) intermediate previous slide reciprocal translocation 13.6 13.5::13.2 13.3 19.4 19.2::1.2 1.1 22.1 22.5 22 22.5 22.1 19.7 19.6::11.5 11.2::11.9 11.10 HyA22 NLE22b NLE8

  3. 2 6 24 24 27 2.1 2.3 2.4 2.6 2.1 2.3::6.3 6.4 6.5 6.6 NLE 3 - 7b- 18 reciprocal translocation 6.1 6.2 6.3 6.4 6.1 6.2::2.4 2.6 2.7 2.9::24.3 24.5 inversion 2.7 2.11 6.5 6.6 27.3 27.2 27.1 27.3 27.2::2.10 2.9::24.2 24.1 27.1 27.2::2.10 2.11 24.1 24.2::2.9 2.10 2.11 NLE18 NLE3 HyA2 HyA6 NLE7A NLE7b 6.1 6.2::2.4 2.5 2.6 reciprocal translocation 6 Robertsonian Fusion in NLE/SSY/HLA ancestor 27.3 27.1 2.7 2.8 2.9 2.10 2.11 27 2 27.3 27.1 24.1 24.2 24.5 24.1 24.2::2.9 2.10 2.11 24.1 24.5 27.1 27.3 intermediate HyA27 T2/6 HyA24 intermediate NLE7a

  4. 23 NLE 2 - 4 - 6 - 10 - 12- 15- 16 4.1 4.3 5.1 5.2 23.1 23.2 fusion 14.1 14.2 14.3 14.4 23.1 23.2 NEC 14.1 14.2 14.3 14.4 4.4 4.7 5.3 5.7 14 HyA23 HyA14 NLE6 NLE2 HyA4 NLE4 HyA5 9.1 9.4 10.1 10.3 7.1 7.2 7.3 7.5 7.1 7.2 7.3 7.5 12.1 12.4 7 NEOCEN 10.4 10.6 NEC 9.5 9.8 12.5 12.6 NLE10 HyA9 NLE12 HyA12 NLE16 HyA10 HyA7 NLE15

  5. 8 15 NLE 5 - 9 18.1 18.4::18.9 18.7::8.2 8.3 8.4 8.8 8.1 8.2 8.8 reciprocal translocation 18.1 18.3 18.4 18.9 18.1 18.3 18.4::18.9 18.7 18.6 18.5 NEC inversion 18 18 HyA18 HyA18(inv) HyA8 NLE5 intermediate pericentric inversion fusion 8.1 8.2::18.7 18.5::15.2 15.1 15.3 15.5 8.1 8.2::18.7 18.6 18.5 15.1 15.2 15.5 15.1 15.2 15.5 8 18 15 intermediate HyA15(inv) HyA15 intermediate NLE9

  6. 20.6 20.4 20.3 20.2::1.7 1.8 NLE11 - 13 - 17 19.1 19.2::1.2 1.4 NLE13 19.1 19.2::1.2 1.4 1.5 1.6::16.5 16.1 reciprocal translocation 1.5 1.6 1.7 1.8 1 20.1 20.2 20.3 19.1 19.2::1.2 1.4 20.4 20.6 20 NLE17 1 reciprocal translocation HyA20 16.1 16.5 16.6 16.7 16.9 T1(1/19) intermediate see NLE1b(I) 16 1.5 1.6 1.7::20.2 20.1 20.1 20.2::1.7 1.6:16.5 HyA16 20 16.6 16.7 16.9 T1(1/19)/20 intermediate NLE11

  7. NLE14 - 19 3.1 3.2:;3.17 3.15 3.14.2::3.5 3.2::3.17 3.19 3.1 3.2 3.5::3.14.2 3.15 3.17 3.19 inversion 3.1 3.5 3.8 Loop and excission NEC 3 NLE19 3 3.9 3.14.1 3.14.2 3.19 intermediate 3.13.2 3.14.1::3.5 3.8 3.9 3.10::3.12.1 3.10::3.12.1 3.13.1 3.13.2 3.14.1::3.5 3.8 3.5::3.14.1 3.8 inversion 3.9 3.10 3.11 3.12 3.13.1 3 3.9 3.13.2 3.13.1 NLE14 intermediate

  8. 17 21 25 NLE20 - 21 - 23 - 24 - 25 - X Robertsonian translocation inversion 25.4 25.1 17.4 17.3 17.2 17.1::17.4 17.7 28.1>2 17.1 17.2 21.1 21.2 25.1 25.4 28.3 28.4 17.3 17.4 17.7 21.1 21.2 HyA25 NLE23 HyA28 HyA21 NLE20 NLE21 HyA21 X.1 X.2::X.3 X.1 X.2 X.3 X.4 X.2::X.3 X.4 inversion 26.1 26.2 29.1 29.3 NLE24 HyA29 NLE25 HyA26 HyAX NLEX

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