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Supplementary Figure 1

Supplementary Figure 1. Supplementary Figure 2. Supplementary Table 1: Classification of patients based on receptor and disease status. Supplementary Table 2 Comparison between two detection techniques. Abbreviations: CSV= Cell-surface vimentin, CK= Cytokeratin,.

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Supplementary Figure 1

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  1. Supplementary Figure 1

  2. Supplementary Figure 2

  3. Supplementary Table 1: Classification of patients based on receptor and disease status

  4. Supplementary Table 2 Comparison between two detection techniques Abbreviations: CSV= Cell-surface vimentin, CK= Cytokeratin,

  5. Supplementary Table 3 Concordances between CSV and CellSearch detection techniques Abbreviations: CSV= Cell-surface vimentin, CTC= Circulating tumor cells.

  6. Supplementary Table 4: Receptor based classification for individual samples with stable/progression status as determined by both techniques CSV: Cell-surface vimentin; CTCs: Circulating tumor cells; ER: Estrogen receptor; PR: Progesterone receptor ; HER2: HER2/neu receptor; Triple negative: ER- PR- HER2-; Luminal A: ER/PR+ HER2-Luminal B: ER/PR+ HER2+, HER2 Type: ER/PR- HER2+

  7. Supplementary Table 5: Analysis of Sensitivity, Specificity, Positive Predictive Value, and Negative Predictive Value based on receptor status of patients CSV: Cell-surface vimentin Summation: sum of CTC counts from 84-1 and CellSearch methods. Triple negative: ER- PR- HER2-; Luminal A: ER/PR+ HER2-Th 5 indicates a threshold of 5 CTCs/ 7.5 mL as cutoff. Th 8 indicates a threshold of 8 CTCs/ 7.5 mL as cutoff.

  8. Supplementary Table 6: Analysis of Nuclear EpCAM Status

  9. Supplementary Table 7: Sensitivity, Specificity, Positive prediction and Negative prediction values for Nuclear EpCAM method

  10. Supplementary Table 8: Clinical parameters, disease status and CTC counts from patients

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