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Oxytocin in mammals

Abrar Al-Shaer, Suraj Madiraju, Briana Block, Rashon Mack. Oxytocin in mammals. Cellular Response. It promotes/causes contractions of the uterus and aids in milk release during lactation. Oxytocin is released to the target cells-myometrial (uterus contractions) & myoepithelial (milk release )

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Oxytocin in mammals

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  1. Abrar Al-Shaer, Suraj Madiraju, Briana Block, Rashon Mack Oxytocinin mammals

  2. Cellular Response • It promotes/causes contractions of the uterus and aids in milk release during lactation. • Oxytocin is released to the target cells-myometrial (uterus contractions) & myoepithelial (milk release) • It is a hormone that acts like a neurotransmitter because it is produced by nerve cells and electrical signals cause it’s release from the hypothalamus to the pituitary gland fro secretion. • Sensory neurons (ex: sense contractions) in the brain stimulate the release of the oxytocin hormone into the blood—which is secreted by the posterior pituitary.

  3. Gland & Chemical • Secreted from posterior pituitary gland, after being produced by the hypothalamus

  4. Lipid or Peptide Based • Peptide hormone • (acts like neurotransmitter)

  5. Feedback Loop • It is a positive feedback loop

  6. Oxytocin Pathway • Oxytocin binds to the oxytocin receptor and starts a signal transduction pathway • It activates the second messenger, PLC • Occurs in a myometrial cell

  7. Alteration in Pathway • If there is an alteration in the pathway contractions won’t occur, so a C-section would be required

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