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Ageing and immunization. Roman Prymula University Hospital Hradec Kralove. Why immunization of adults ?. Ratio of age cohorts 0-14 and 65+ in the Czech population in time. Adult population is exposed to: Vaccine preventable diseases Chronic diseases and comorbidities
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Ageingand immunization Roman Prymula University Hospital Hradec Kralove Prague 31 May 2012
Whyimmunizationofadults? Ratio ofagecohorts 0-14 and 65+ in the Czech population in time • Adultpopulationisexposed to: • Vaccinepreventablediseases • Chronicdiseases and comorbidities • Ageing • Waningimmunity and immunosenescence • New vaccinesforadults and olderpeople • VZV, HSV, CMV, Alzheimer disease, Parkinson disease, variouscarcinomas • Vaccinationcoverage in adultsislow • Perception on vaccinesislow ČSÚ: Projekce obyvatelstva České republiky, availableat: http://www.czso.cz/csu/2004edicniplan.nsf/t/B0001D6145/$File/4025rra.pdf In US 350x more adultsdie on vaccinepreventablediseasesthanchildren! Prague 31 May 2012
Ratio ofolderpeople in population, 2008-2040 (Europe) Age (Years) Age (Years) 3 Kinsella K, He W. US Census Bureau, International Population Reports, P95/09-1, An Aging World: 2008, US Government Printing Office: Washington, DC; 2009.
Risk ofpneumococcaldiseasesdevelopmentismultiplied in chronicilladults Kyaw MH et al. JID 2005; 192: 377-86
Vaccination in adults Boostingafterprimaryschedule in childhood Primaryimmunization in adults and olderpeople Boostingin adults and olderpeople Vaccinationoftravellers Prague 31 May 2012
Higher mortality on pneumonia (communityacquieredincluded) startssince 45th yearofage 609,9 570,9 United Kingdom, Mortality according to age, 2005 Prague 31 May 2012 (WHO Statistics. Mortality Database. http://apps.who.int/whosis/database/mort/table1_process.cfm. Accessed June 10, 2009.)
Conclusion • Risingimportanceofadult and olderpeoplevaccination • Persistentlowcoverageofolderpeople • Implementationofadultimmunizationcalendar • Developmentofnationalguidelines • Accessibility to adultvaccines • Role ofGPs Vaccinationis very importantforpreventionofdiseases and generalyforlifeprotection. Prague 31 May 2012