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RA. LA. A. C. 200. 200. CTL, n=6. CTL, n=14. CHF, n=6. CHF, n=10. 150. 150. Relative to CTL. (Normalized to GAPDH). *. Relative to CTL. (Normalized to GAPDH). 100. *. 100. *. *. 50. *. 50. *. *. *. *. *. *. 0. 0. MyBP-C. P282. P282. MLC2a-P. MyBP-C. P282.

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  1. RA LA A C 200 200 CTL, n=6 CTL, n=14 CHF, n=6 CHF, n=10 150 150 Relative to CTL (Normalized to GAPDH) * Relative to CTL (Normalized to GAPDH) 100 * 100 * * 50 * 50 * * * * * * 0 0 MyBP-C P282 P282 MLC2a-P MyBP-C P282 P282 MLC2a-P MyBP-C MyBP-C D B 250 250 CTL, n=6 CTL, n=14 CHF, n=6 CHF, n=10 200 200 150 150 Relative to CTL (Normalized to GAPDH) Relative to CTL (Normalized to GAPDH) 100 100 50 50 0 0 PP1 PP2A PP1 PP2A On-line Figure 7

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