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TB epidemiology in Thailand. Philippe Glaziou, on behalf of the epi team Bangkok, August 2013. TB in Thailand: key figures (2012). 80,000 new cases 11,000 TB deaths. Thailand among 22 countries with highest TB incidence. TB epidemiology: case notification rate. All forms. Smear pos.
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TB epidemiology in Thailand Philippe Glaziou, on behalf of the epi team Bangkok, August 2013
TB in Thailand: key figures (2012) 80,000 new cases 11,000 TB deaths Thailand among 22 countries with highest TB incidence
TB epidemiology: case notification rate All forms Smear pos
Under-reporting of childhood TB (2010) Under-reporting of childhood TB estimated at 45% of diagnosed cases min(Uc) = 1 – (1 – Ut).(1 – Ub) Uc = under-reporting childhood Ut = overall under-reporting (prevalence survey) Ub = BTB under-reporting of BoE cases
Treatment success 85% global Treatment success target
At risk populations: health workers • Saraburi hospital: n=1800 health workers • average incidence = 206/100,000 person-year • Relative Risk ≈ 1.4
TB mortality (excluding HIV) Adjusted for incomplete coverageand ill-defined causes Raw data from VR
Determinants of TB: economic growth 1997 financial crisis
Determinants of TB: health system performance (U5MR) 13/1000
Good performance of Thailand relative to country income group
Determinants of TB: HIV in 15-49 yr old population Source: UNAIDS 2013
HIV prevalence in TB Source: BTB surveillance
Determinants of TB: rapid aging of the population Population estimates from UN Pop Division, 2013
Impact of TB control? • Cured 525,000 cases since 2000 (79% of 665,000) • Prevented the emergence of MDR-TB • 2006: 1.65% (new), 34.5% (retx), 6.4% (combined) • 2013: 1.89% (new), 16.6% (retx), 3.4% (combined) • Decline in TB incidence and mortality multifactorial • Economic growth, UCS, decline in HIV, TB control,…
Global targets • MDG target 6c met (incidence reverted) • Thailand on track to meeting 50% reduction targets for prevalence and mortality (2015) But … • The burden of TB in Thailand is still high and requires a prioritized public health response