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Collateral Damage From HLA Mismatching

Collateral Damage From HLA Mismatching. Gerhard Opelz. Rejection Treatment During 1 st Year Deceased Donor Kidney Transplants 1990-2012 . +84%. Rejection Treatment During 1 st Year. A+B Mismatches 0 DR MM. DR Mismatches 0 A+B MM. +97%. +57%.

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Collateral Damage From HLA Mismatching

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  1. CollateralDamageFrom HLA Mismatching Gerhard Opelz

  2. Rejection Treatment During 1stYearDeceasedDonorKidneyTransplants 1990-2012 +84%

  3. Rejection Treatment During 1st Year A+B Mismatches 0 DR MM DR Mismatches 0 A+B MM +97% +57%

  4. Steroid Dose at Year 1 (mg/kg/d) A+B Mismatches 0 DR MM DR Mismatches 0 A+B MM

  5. *) > 90-Percentile Transplantation 89: 567-572, 2010

  6. Transplantation 89: 567-572, 2010

  7. Non-Hodgkin LymphomaDeceasedDonorKidneyTransplants HLA-A HLA-B HLA-DR Transplantation 89: 567-572, 2010

  8. Non-Hodgkin Lymphoma – EBV StatusKidneyTransplants 1995-2012 Transplantation 88: 962-67, 2009

  9. Pediatric Recipients Transplantation 90: 292-297, 2010

  10. Osteoporosisat Year 5 +50% Transplantation 91: 65-69, 2011

  11. Hip Fracture +170% Transplantation 91: 65-69, 2011

  12. Death With a Functioning GraftDeceasedDonorKidneyTransplants n=177,584 2% per year 5%

  13. Death With a Functioning Graft Am J Transplant 12: 3031-3038, 2012

  14. Causeof Death Infection Cardiovascular Cancer Am J Transplant 12: 3031-3038, 2012

  15. Death With a Functioning Graft Am J Transplant 12: 3031-3038, 2012

  16. Heart Transplants1990-2011

  17. Heart Transplants1990-2011

  18. LiverTransplants1990-2011

  19. Rejection Treatment First YearLiverTransplants 1990-2011

  20. Death Due toInfectionLiverTransplants 1990-2011

  21. SecondaryEffectsof HLA Mismatches

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