140 likes | 292 Views
FIRST WEEK OF PREGNANCY. Segmentation. Dr. Sherif Fahmy. START OF CLEAVAGE. Fertilization leads to formation of a zygote which is a fertilized ovum surrounded with zona pellucida.
E N D
FIRST WEEK OF PREGNANCY Segmentation Dr. Sherif Fahmy
START OF CLEAVAGE • Fertilization leads to formation of a zygote which is a fertilized ovum surrounded with zona pellucida. • Zygote divides by mitotic division to form 2-cell stage----- 4-cell stage -------- 8-cell stage ------- 16-cell stage --------- 32-cell stage ------ 64-cell stage (morula). • Cells of morula are called blastomere. • Formation of morula takes 3 days through which it is transmitted through the uterine tube. • Zona pellucida prevents adhesion of zygote to uterine tube and prevents separation of cells. Dr. Sherif Fahmy
Formation of Morula • By the end of 4th day, zona pellucida ruptures due to increase in number of blastomeres. • The blastomeres that remain after rupture of zona is called morula. • Fluid enters between cells and forms acavity (blastocele) which separates cells into outer cell mass (trophoblast) and inner cell mass (embryoblast). This stage is called blastocyst which is formed at the 6th day. • Embryoblast forms fetus while trophoblast form placenta, amniotic cavity and umbilical cord. Dr. Sherif Fahmy
BLASTOCYST • It is formed at the 6th day from morula which a cavity develop a cavity (blastocele). • Cells of blastocyts separates into outer cell mass and inner cell mass. • Outer cell mass (trophoblast) is responsible for absorption of nutritive material which is uterine fluid (uterine milk). • Inner cell mass (embryoblast) will form the embryo Dr. Sherif Fahmy