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Multicystic dysplastic kidney. 1/2000 Common cause of abdominal mass in newborn Contralateral VUR:15% Contralateral hydronephrosis:5-10%. Sonography: kidney replaced by multiple cyst of varying size, no communication, no identifiable parenchyma. Renal scan: no function Annual followed up
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Multicystic dysplastic kidney • 1/2000 • Common cause of abdominal mass in newborn • Contralateral VUR:15% • Contralateral hydronephrosis:5-10%
Sonography: kidney replaced by multiple cyst of varying size, no communication, no identifiable parenchyma. • Renal scan: no function • Annual followed up • Nephrectomy: abdominal mass, any cyst enlarged, hypertension, stromal core increased in size
Multicystic dysplastic kidney • Simple • Complex: combined with other GU abnormality (duplication of the collecting system, dilation of the ureter or renal pevis, posterior urethral valve, neurogenic bladder, uretocele, cryptorchism)
Simple MCDK had an incidence of UTI similar to in children without MCDK(5%) • Complex MCDK : increased risk of UTI: 28% • Bilateral or unilateral MCDK with associated GU abnormality place the patietn at the incrased risk of UTI independent of VUR Clinical course and outcome for children with MCDK , Pedriatr Nephrol(2000)
Eur J Pediatr(1998) • Multicystic kidney shrink in the first 2 years of life • Contralateral kidney maintain a normal renal function as a consequence of progressive compensatory hypertrophy
Clinical feature of unilateral MCKD in childEur J Pediatr(1998) • 40/204: nephrectomy • 164/204; conservative tx • Slight renal function impairement • No difference in the number of complication in two group.