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12-01 - 010121

Opportunity Europe. Building a European platform. 12-01 - 010121. Fundamentals. EGA 2006 market review: on average 50% all medicines dispensed to patients in Europe are generics. Market share by value: 18% Top 20 generic molecules: 3.95billion Euro But: unequal spread over countries.

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12-01 - 010121

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  1. Opportunity Europe Building aEuropean platform 12-01 - 010121

  2. Fundamentals • EGA 2006 market review: on average 50% all medicines dispensed to patients in Europe are generics. Market share by value: 18% • Top 20 generic molecules: 3.95billion Euro • But: unequal spread over countries. • Greying population accross Europe. • Need for sustainable healthcare systems. • generics will build market share. • Increased competition will force patented pharma to reduce prices. • Indian pharma: organic growth or acquisition will allow to take market share.

  3. European Generics market Room to grow 12-01 - 010121

  4. Comparing selected generics markets (ega generics)

  5. Generics on the Belgian market (source:febelgen)

  6. Comprehensive analysis

  7. EU Generics market • Different penetration rates • Different reimbursement systems • Fragmented approval market • Fragmented marketing effort? • But what about logistics?

  8. Asia Co case study Previous set-up: • Fragmented deliveries by country or customer • Multiple testing ulabs & carriers • SEA freight transhipped via Rotterdam or Southampton to Ireland for Batch release and than truckedto the destination country. • No IT connectivity • Limited control over the supply chain 09-07 - 040624

  9. Asia Co case study New set-up: • Warehouse located in the centre of the main business markets • consolidated deliveries for multiple countries into Belgium, both for sea & air. Sea freight arriving in Zeebrugge and Antwerp, airfreight landing in Brussels • reduced amount of labs • European SOP’s • IT interfaces with NYK • Conditioned transport • Full control till delivery European Distribution Centre 09-07 - 040624

  10. United Kingdom: second largest pharmaceutical producer in Europe production value in million euro, 2003 Pharmaceutical productionin UK: 21,685 million euro Pharmaceutical productionin Belgium: 4,245 million euro Source: European Federation of Pharmaceutical Industries and Associations (EFPIA); The Pharmaceutical Industry in Europe, Key data 2005 Update, p. 6 02-06 - 160302

  11. UK production versus Belgian export • UK produces 5 times more pharmaceuticals than Belgium BUT • Belgium exports 1.3 times more pharmaceuticals than UK! 02-06 - 160303

  12. Belgium: largest exporter of pharmaceuticals export in million euro, 2003 Pharmaceutical exportfrom UK: 17,234 million euro Pharmaceutical exportfrom Belgium: 22,597 million euro Source: European Federation of Pharmaceutical Industries and Associations (EFPIA); The Pharmaceutical Industry in Europe, Key data 2005 Update, p. 14; Others: Greece, Norway, Finland, Portugal 02-06 - 160304

  13. Belgium: largest importer of pharmaceuticals import in million euro, 2003 Pharmaceutical importinto Belgium: 23,216 million euro Source: European Federation of Pharmaceutical Industries and Associations (EFPIA); The Pharmaceutical Industry in Europe, Key data 2005 Update, p. 15; Others: Greece, Norway, Finland, Portugal 02-06 - 160305

  14. Belgium, Europe’s largest distribution center • Belgium is not only the largest exporterbut also the largest importerof pharmaceuticals in Europe THUS • Belgium is Europe’s largest distribution center for pharmaceuticals 02-06 - 160306

  15. Pharmaceuticals: Flanders and Ireland • Some examples: • Ireland and Flanders: a partnership of productionand distribution • Belgium imports about 60% of total Irish pharmaceutical exports 02-06 - 160309

  16. Belgium: the pharmaceutical distributor of Ireland Belgian import of Irish pharmaceuticalsversus totalIrish export of pharmaceuticals million euro 62% 56% Belgium imports about 60% of total Irish pharmaceutical exports Source: Irish exports: Statistical Yearbook of Ireland 2004, p. 286 Statistical Yearbook of Ireland 2002, p. 280 Belgian imports: Comext Database Eurostat 02-06 - 160310

  17. Production in Ireland – Distribution in Flanders Pfizer Ireland 5 production sites Flanders 2 production sites 2 distribution centers Mechelen New Logistics CenterMechelen (since 2006) Brussels European Logistics CenterBrussels Airport 02-06 - 160312

  18. Production in Ireland – Distribution in Flanders Schering-Plough Ireland 3 production sites Flanders 1 production site 1 distribution center Largest Production Plant in Europe Heist-op-den-Berg Bray Boortmeerbeek Avondale New Logistics Center (since 2006) Brinny 02-06 - 160313

  19. Production in Ireland – Distribution in Flanders Johnson&Johnson Belgium 6 production sites 1 distribution center3 research centers Ireland 1 production site Janssen Pharmaceutica Production and Research Center Beerse Geel Mechelen 4 production plants 1 production site 2 research centers Courcelles New Logistics Center (since 2005) Little Island Plant 02-06 - 160314

  20. Logistic providers for the pharmaceutical sector in FlandersNYK Logistics Belgium NYK Logistics Belgium Keetberglaan 2 Haven 1089 B-9120 Melsele Belgium tel: +32.3.451.37.75 fax: +32.3.570 69 12 Ann.d’hondt@be.nyklogistics.co www.nyklogistics.com Antwerp 02-06 - 160317

  21. Logistic providers for the pharmaceutical sector in FlandersExcel Belgium Exel Presence Belgium Exel Belgium Life Sciences Logistics Office Weg naar Zwartberg 237 B-3660 Opglabbeek Belgium tel: +32.89.365.400 fax: +32.89.365.410 www.exel.com/exel/home/regions/emea/belgium/en One of Exel’s customers in Opglabbeek (Belgium): Terumo www.terumo.co.jp Exel Wommelgem Exel Mechelen Exel Opglabbeek Exel Vilvoorde Exel Tongeren Exel Nivelles 6 Operating Sites: 3 Technology 2 Retail 1 Health Care Airfreight - SeafreightOffices in: Zaventem, Deurne, Antwerp 02-06 - 160315

  22. Logistic providers for the pharmaceutical sector in FlandersDHL Solutions DHL Solutions Eppegemsesteenweg 31-33 B-1850 Grimbergen tel: +32.2.255.12.11 fax: +32.2.251.69.30 www.dhl.be Grimbergen 02-06 - 160316

  23. Logistic providers for the pharmaceutical sector in FlandersBax Global • Bax Global • Antwerp Ocean Services • Karveelstraat 5 • B-2030 Antwerp • Belgium • tel: +32.3.646.05.11 • fax: +32.3.645.58.82 • Brussels Airport • Building 755 • B-1931 Brucargo • Belgium • tel: +32.2.752.95.50 • fax: +32.2.751.85.32 • www.baxglobal.com Antwerp Kortrijk Brussels • Kortrijk Transport Zone • Transportcentrum LAR K25 • B-8930 Rekkem • Belgium • tel: +32.56.43.91.32 • fax: +32.56.42.13.38 02-06 - 160317

  24. Logistic providers for the pharmaceutical sector in FlandersTNT Logistics TNT Logistics Zandvoortstraat 16 Industriezone Noord II B-2800 Mechelen Belgium tel: +32.15.28.89.00 fax: +32.15.28.89.01 www.tntlogistics.be Mechelen 02-06 - 160318

  25. Logistic providers for the pharmaceutical sector in FlandersSomitomo Warehouse Sumitomo Warehouse Sumitomo Warehouse Europe Fotografielaan 37-39 B-2610 Wilrijk (Antwerp) Belgium tel: +32.3. 825.15.15 fax: +32.3. 825.15.45 www.sumitomo-soko.co.jp Wilrijk 02-06 - 160319

  26. Logistic engineering companies for the pharmaceutical sector in FlandersJ-Tec and Katoen Natie J-TEC Lieven Gevaertstraat 11 B-2950 Kapellen Belgium tel.: +32.3.660.51.11 fax: +32.3.660.51.10 www.j-tec.com Daughter company of: Katoen Natie Van Aerdtstraat 33 B-2060 Antwerp Belgium tel: +32.3.221.68.11 fax: +32.3.221.68.10 www.katoennatie.com Kapellen Antwerp 02-06 - 160320

  27. Logistic engineering companies for the pharmaceutical sector in FlandersEurinpro Belgium Eurinpro Belgium Kasteel van Bever Boechoutlaan 221 B-1853 Strombeek-Bever Belgium tel: +32.2.263.40.00 fax: +32.2.263.40.40 www.eurinpro.com Strombeek-Bever 02-06 - 160321

  28. To contact: Peter.verplancken@fitagency.be

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