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PHYSIOLOGY

PHYSIOLOGY. REPRODUCTION. Oogenesis: Egg Cell Formation. Oogonia mitosis ceases before birth At birth: only primary oocytes – suspended in prophase of meiosis I (= prophase I). Oogenesis after Birth:. At puberty: ↑ estrogen initiates ovarian cycle. ovulation.

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PHYSIOLOGY

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  1. PHYSIOLOGY REPRODUCTION

  2. Oogenesis: Egg Cell Formation Oogonia mitosis ceases before birth At birth: only primary oocytes – suspended in prophase of meiosis I (= prophase I)

  3. Oogenesis after Birth: At puberty: ↑ estrogen initiates ovarian cycle ovulation 2nd meiotic division completed after fertilization

  4. Growth and Aging • Puberty (  GnRH) • in girls = menarche • Average 12 y • In boys, later (harder to pinpoint a time) • Menopause • Irregular menstrual periods and cessation • Andropause • Similar drop in androgens

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  6. Biosynthetic Pathway for Steroid Hormones Theca cells Synthesize androgens Granulosa cells convert androgens to estrogen diffusion

  7. Spermatogenesis • Seminiferous tubules • Sertoli cells: androgen binding protein blood testes barrier etc. • Leydig cells testosterone vs. DHT

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