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Schistosomiasis Control Initiative (SCI)

Schistosomiasis Control Initiative (SCI). A brief overview of SCI past and current activities SCI Open Day June 27 2013 Director Professor Alan Fenwick OBE PhD Department of Infectious Disease Epidemiology Imperial College Faculty of Medicine St Mary’s University of London. Welcome.

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Schistosomiasis Control Initiative (SCI)

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  1. SchistosomiasisControl Initiative (SCI) A brief overview of SCI past and current activities SCI Open Day June 27 2013 Director Professor Alan Fenwick OBE PhD Department of Infectious Disease Epidemiology Imperial College Faculty of Medicine St Mary’s University of London

  2. Welcome Welcome to the members of the SCI Advisory Board Chairman, Sir Roy Anderson Justine Fraine Clint Evans Sam Zaramba David Heymann Stuart Smith Richard Viner Lorenzo Savioli David Crompton Lord Andrew Stone Peter Dranfield Apologies from Profs Neil Ferguson and ElioRiboli Welcome to all present: guests, partners, and donors and especially staff from overseas – Dr Narcis Kabatereine, Dr Dhekra Annuzaili and from Ethiopia OumerShafi

  3. The SCI aims to assist implementation of control of NTDs to national scale in Africa • Based at Imperial College London within the School of Public Health • Established in 2002 • SCI has moved through 4 phases • 2002-07 Bill and Melinda Gates support • 2007-10 Add in USAID/RTI, Geneva Global • 2010-13 DFID plus private donations • 2013 - Expansion towards elimination

  4. Within the College • Imperial College has “charity exempt” status • IC Trust gives us charity status in UK • Our financial income is ring fenced • UK Coalition against NTDs • London Centre for NTDs

  5. Recent wider funding sources • GNNTDC funded projects in Uganda and Yemen (SCI Founder member) – Yemen support now funded by ENDFUND • Yemen World Bank partnership 2010-2015 • Gates funding (neuro-cysticercosis in 3 countries) • ENDFUND/Geneva Global grant (2010-13) for Rwanda • ENDFUND small grant for Zimbabwe • DFID award ICOSA (2010-2015) • SCORE – 3 grants for operational research (Mozambique and Niger) (2010-2015) • Sightsavers – partnership on mapping and implementation in Nigeria • Private donations from US and UK public (ongoing)

  6. Collaboration Partnership with : • Developing World Health (fund raising) • PCD (Imperial College) - Ethiopia • Deworm the World (school health) • Sightsavers (UK NTD Coalition) • CNTD Liverpool (DFID ICOSA) • GSK (albendazole donation) • WHO and Merck Serono (pzq donation) • Natural History Museum/SCORE (Zanzibar) • SCORE (Niger and Mozambique) • www.givingwhatwecan.org • www.givewell.org

  7. SCI control programmes in Africa 2012-2016 Yemen World Bank and ENDFUND Mauritania Niger Senegal Nigeria Ethiopia Liberia Uganda Cote D’Ivoire DRC Rwanda – SCI/ENDFUND Tanzania Malawi Burundi Zambia Zim Madagascar Mapping and development of control in DRC, Mauritania, Senegal, Ethiopia, Zimbabwe And Madagascar Mozambique

  8. June 2012 – June 2013 We have been implementing our praziquantel and albendazole treatments in 8 countries as per DFID contract in partnership with Liverpool and Crown Agents. (75 million treatments over 5 years) We have been collecting data and treating in Niger and Mozambique as grantee partners in the SCORE project at UGA We now have in place 4 years funding for Burundi from a private donor and ENDFUND support for Rwanda for 3 years. MoH carry out twice a year deworming of school children and annual praziquantel treatment where indicated

  9. June 2012 - June 2013 Recommendations on their websites from both www.Givingwhatwecan.org and www.Givewell.org have led to generous donations from the British & US public. With this funding we have: • Assisted Senegal to expand mapping • Assisted round 2 treatments in Yemen (10 million treatments this year alone) • Transfered funding to Ethiopia for • 1.5 million treatments spread over all health regions Ethiopia, • a launch of the national plan plus NTD symposium in Addis Ababa in June 2013 • Pledged funding for schistososmaisis and STH mapping nationally during 2013 with EHNRI,

  10. Follow up from January 2012 Since the January 30th 2012 meeting in London (The London Declaration): • Meeting at World Bank in December 2012 • WHA resolution on elimination of NTDs May 2013 • Scorecard towards elimination developed

  11. 2012 and 2013 treatments

  12. And the future ?Elimination by 2020 ? We plan to consolidate our support in each of the “SCI” countries so that they reach and sustain national coverage We will pursue fund raising opportunities as they arise to increase resources going to NTD control With increased support from DFID promised for 2013-2017 we anticipate a closer partnership with PCD and an increase in treatments in the existing countries, plus expansion into Ethiopia and DRC We are working more closely with USAID and their contractors, and with Deworm the World to avoid duplication of donations

  13. Advocacy Membership of WHO Scientific and Technical Advisory Group (STAG) Director of UK Coalition (Wendy Harrison) London Centre (partners) APPMG (Author of NTD report) ENDFUND (Technical Advisory Board)

  14. Publications and Teaching • Approximately 100 publications have been published or are in press in 2005-2011 (list available) • Staff teach in B.Sc. Module (Life Sciences) and Bio-Medical Sciences • B.Sc. For 4th medical students (Hepatology and Global health) • M.Sc. course at Imperial College London • Short course on Global Health at Imperial College (this week !) • Supervise several B.Sc. and M.Sc. students with their projects

  15. To achieve elimination • Improved education and coverage especially in “difficult countries” • Water and sanitation • Reduction in poverty • Socio-economic development

  16. Population requiring preventive chemotherapy ~ 243 million ~ 873 million ~ 1 410 million ~ 127 million ~ 281 million 77.1 Proportion, % 41.8 31.1 13.7 13.3 Soil-transmitted helminthiases Lymphatic filariasis Schistosomiasis Onchocerciasis Trachoma Proportion of PC for schistosomiasis, soil-transmitted helminthiases, lymphatic filariasis, onchocerciasis and trachoma, 2011

  17. Where we can get with existing tools and strategies Where we can get with new tools and strategies Where we are now 2020 Goals Diseases Targeted For Control Diseases Targeted For Elimination Guinea worm Leprosy Lymphatic filariasis Blinding trachoma Sleeping sickness Schistosomiasis River blindness Soil-Transmitted Helminthes Chagas Visceral Leishmaniasis

  18. Acknowledgements To the SCI staff, past and present To Sir Roy Anderson who has chaired the Advisory Board annually since we started To Professor Elio Riboli and Neil Ferguson for their support DIDE administrator Ruth Tipples To all our partners especially in Liverpool.

  19. In country - among many others • In Uganda - Drs. Narcis Kabatereine, Edridah Tukahebwa and the VCD staff; Dr. Sam Zaramba • In Tanzania – Drs. Ursuline Nyandindi, Mweli Malacela, Peter Kilima, Upendo Mwingira • In Zanzibar - Dr. Khalfan Mohammed; • In Zambia – Dr. Mutale Nsakashalo • In Niger – Drs. Amadou Garba, Ali Djibo • In Rwanda – Drs Irenee Umulisa, Corine Karema • In Burundi – Drs Dismas Baza; Jean-Paul Nyarushatsi; Onésime Ndayishimiye; Ndyabanirwa Janvier; Didace Mbaririmbanyi • In Senegal – Dr Idrissa Talla • In Ethiopia – Mr Oumer Shafi • In Yemen – Dr Dhekra Annuzaili • In Malawi – Dr Samuel Jemu • In Cote D’Ivoire – Dr Aboulaye Meite, Professor Elizier N’Goran • And WHO staff of NTD Department • a.fenwick@imperial.ac.uk

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