AP Biology

1. AP Biology Exam Critical Concepts Evolution: Chapters 22-26

2. Chapter 22 Introduction to Evolution • Darwin perceived adaptation to the environment and the origin of new species as closely related processes • Biologists have concluded that this is indeed what happened to the Galápagos finches • “descent with modification” summarized Darwin’s perception of the unity of life • refers to the view that all organisms are related through descent from an ancestor that lived in the remote past

3. Chapter 22 Introduction to Evolution cont. • Darwin’s 4 observations: • Members of a population often vary greatly in their traits • Traits are inherited from parents to offspring • All species are capable of producing more offspring than the environment can support • Owing to lack of food or other resources, many of these offspring do not survive

4. Chapter 22 Introduction to Evolution cont. • From his observations he drew 2 inferences: • Inference #1: Individuals whose inherited traits give them a higher probability of surviving and reproducing in a given environment tend to leave more offspring than other individuals • Inference #2: This unequal ability of individuals to survive and reproduce will lead to the accumulation of favorable traits in the population over generations

5. Chapter 22 Introduction to Evolution cont. • Individuals do not evolve; populations evolve Natural selection can only increase or decrease heritable traits in a population • Adaptations vary with different environments • Two examples for natural selection • The effect of differential predation on guppy populations • The evolution of drug-resistant HIV • The use of drugs to combat HIV selects for viruses resistant to these drugs • HIV uses the enzyme reverse transcriptase to make a DNA version of its own RNA genome

6. Chapter 22 Introduction to Evolution cont. • The drug 3TC is designed to interfere and cause errors in the manufacture of DNA from the virus • Some individual HIV viruses have a variation that allows them to produce DNA without errors • These viruses have a greater reproductive success and increase in number relative to the susceptible viruses • The population of HIV viruses has therefore developed resistance to 3TC • The ability of bacteria and viruses to evolve rapidly poses a challenge to our society

7. Chapter 22 Introduction to Evolution cont. • Natural selection does not create new traits, but edits or selects for traits already present in the population • The local environment determines which traits will be selected for or selected against in any specific population • The Darwinian view of life predicts that evolutionary transitions should leave signs in the fossil record • Paleontologists have discovered fossils of many such transitional forms

8. Chapter 22 Introduction to Evolution cont. • Homologous structures: anatomical resemblances that represent variations on a structural theme present in a common ancestor • Vestigial structures: remnants of features that served important functions in the organism’s ancestors The Appendix Wisdom teeth The Tail Bone The Arrector Pili • Examples of homologies at the molecular level are genes shared among organisms inherited from a common ancestor

9. Chapter 22 Introduction to Evolution cont. • The Darwinian concept of an evolutionary tree of life can explain homologies • Evolutionary trees : hypotheses about the relationships among different groups • can be made using different types of data, for example, anatomical and DNA sequence data • Convergent evolution: the evolution of similar, or analogous,features in distantly related groups • Analogous traits arise when groups independently adapt to similar environments in similar ways • Biogeography: geographic distribution of species,

10. Chapter 23 Evolution of populations • One misconception is that organisms evolve during their lifetimes • Natural selection: acts on individuals, but only populations evolve • Genetic variations in populations contribute to evolution • Variation in individual genotype leads to variation in individual phenotype • Not all phenotypic variation is heritable • Natural selection can only act on variation with a genetic component

11. Chapter 23 Evolution of populations cont. • Population geneticists measure polymorphisms in a population by determining the amount of heterozygosity at the gene and molecular levels • Average heterozygosity: the average percent of loci that are heterozygous in a population • Geographic variation: occurs between gene pools of separate populations or population subgroups • Cline: a graded change in a trait along a geographic axis • Examples of geographic variation occur here

12. Chapter 23 Evolution of populations cont. • Mutations: changes in the nucleotide sequence • cause new genes and alleles to arise • Only mutations in cells that produce gametes can be passed to offspring • Point mutations: A change in one base in a gene: • noncoding regions of DNA are often harmless • might not affect protein production because of redundancy in the genetic code • change in protein production are often harmful • change in protein production can sometimes increase the fit between organism and environment

13. Chapter 23 Evolution of populations cont. • Chromosomal mutations that delete, disrupt, or rearrange many loci are typically harmful • Duplication of large chromosome segments is usually harmful • Duplication of small pieces of DNA is sometimes less harmful and increases the genome size • Sexual reproduction can shuffle existing alleles into new combinations • recombination of alleles is more important than mutation in producing the genetic differences that make adaptation possible

14. Chapter 23 Evolution of populations cont. • Population: localized group of individuals capable of interbreeding and producing fertile offspring • Gene pool: all the alleles for all loci in a population

15. Chapter 23 Evolution of populations cont. • The frequency of an allele in a population can be calculated: • Diploid organisms: the total number of alleles at a locus is the total number of individuals x 2 • The total number of dominant alleles at a locus is 2 alleles for each homozygous dominant individual plus 1 allele for each heterozygous individual • same logic applies for recessive alleles • p and q are used to represent their frequencies • The frequency of all alleles in a population will add up to 1 For example, p + q = 1

16. Chapter 23 Evolution of populations cont. • Hardy-Weinberg principle: describes a population that is not evolving • If a population does not meet the criteria of the principle, it can be concluded that the population is evolving • States that frequencies of alleles and genotypes in a population remain constant from generation to generation • In a given population where gametes contribute to the next generation randomly, allele frequencies will not change • Describes the constant frequency of alleles in such a gene pool

17. Chapter 23 Evolution of populations cont. • Hardy-Weinberg formula: • If p and q represent the relative frequencies of the only two possible alleles in a population at a particular locus, then p2 + 2pq + q2 = 1 • where p2 and q2 represent the frequencies of the homozygous genotypes and 2pq represents the frequency of the heterozygous genotype

18. Chapter 23 Evolution of populations cont. • The Hardy-Weinberg theorem describes a hypothetical population • In real populations, allele and genotype frequencies do change over time • The five conditions for non-evolving populations are rarely met in nature: • No mutations • Random mating • No natural selection • Extremely large population size • No gene flow

19. Chapter 23 Evolution of populations cont. • Three major factors alter allele frequencies and bring about most evolutionary change: • Natural selection • Genetic drift • Gene flow • Genetic drift: how allele frequencies fluctuate unpredictably from one generation to the next • tends to reduce genetic variation through losses of alleles

20. Chapter 23 Evolution of populations cont. • Founder effect: a few individuals become isolated from a larger population • Allele frequencies in the small founder population can be different from those in the larger parent population • Bottleneck effect: a sudden reduction in population size due to a change in the environment • resulting gene pool may no longer be reflective of the original population’s gene pool • If the population remains small, it may be further affected by genetic drift

21. Chapter 23 Evolution of populations cont. • Effects of Genetic Drift: • is significant in small populations • causes allele frequencies to change at random • can lead to a loss of genetic variation within populations • can cause harmful alleles to become fixed

22. Chapter 23 Evolution of populations cont. • Gene flow: consists of the movement of alleles among populations • Alleles can be transferred through the movement of fertile individuals or gametes (for example, pollen) • tends to reduce differences between populations over time • more likely than mutation to alter allele frequencies directly

23. Chapter 23 Evolution of populations cont. • Relative fitness: the contribution an individual makes to the gene pool of the next generation, relative to the contributions of other individuals • Selection favors certain genotypes by acting on the phenotypes of certain organisms • Sexual selection is natural selection for mating success • It can result in sexual dimorphism, marked differences between the sexes in secondary sexual characteristics

24. Chapter 23 Evolution of populations cont. • Three modes of selection: • Directional selection favors individuals at one end of the phenotypic range • Disruptive selection favors individuals at both extremes of the phenotypic range • Stabilizing selection favors intermediate variants and acts against extreme phenotypes • Neutral variation: genetic variation that appears to confer no selective advantage or disadvantage

25. Chapter 23 Evolution of populations cont. • Heterozygote Advantage: occurs when heterozygotes have a higher fitness than do both homozygotes • will tend to maintain two or more alleles at that locus • The sickle-cell allele causes mutations in hemoglobin but also confers malaria resistance • Frequency-dependent selection: the fitness of a phenotype declines if it becomes too common in the population • Selection can favor whichever phenotype is less common in a population

26. Chapter 24 Evolution of species • Speciation: origin of new species • Microevolution: adaptations that evolve within a population • confined to one gene pool • Macroevolution: evolutionary change above the species level • Species: group of populations whose members have the potential to interbreed in nature and produce viable, fertile offspring • do not breed successfully with other populations • Hybrids: offspring of crosses between different species

27. Chapter 24 Evolution of species cont. • Prezygotic barriers: block fertilization from occurring by: • Impeding different species from attempting to mate • Preventing the successful completion of mating • Hindering fertilization if mating is successful • Types • 1. Habitat isolation: Two species encounter each other rarely, or not at all, because they occupy different habitats, even though not isolated by physical barriers

28. Chapter 24 Evolution of species cont. • 2. Temporal isolation: Species that breed at different times of the day, different seasons, or different years cannot mix their gametes • 3. Mechanical isolation: Morphological differences can prevent successful mating • 4. Behavioral isolation: Courtship rituals and other behaviors unique to a species are effective barriers • 5. Gametic isolation: Sperm of one species may not be able to fertilize eggs of another species

29. Chapter 24 Evolution of species cont. • Postzygotic barriers: prevent the hybrid zygote from developing into a viable, fertile adult: • Reduced hybrid viability: Genes of the different parent species may interact and impair the hybrid’s development • Reduced hybrid fertility: Even if hybrids are vigorous, they may be sterile • Hybrid breakdown: Some first-generation hybrids are fertile, but when they mate with another species or with either parent species, offspring of the next generation are feeble or sterile

30. Chapter 24 Evolution of species cont. • Morphological species concept: defines a species by structural features • Ecological species concept: defines a species in terms of its ecological niche • Phylogenetic species concept: defines a species as the smallest group of individuals on a phylogenetic tree • Speciation: the evolution of a new species

31. Chapter 24 Evolution of species cont. • Speciation: occurs one of two ways 1. Allopatric (“Other Country”) Speciation: Gene flow is interrupted or reduced when a population is divided into geographically isolated subpopulations • The definition of barrier depends on the ability of a population to disperse • Separate populations may evolve independently through mutation, natural selection, and genetic drift • Even if contact is restored between populations, interbreeding is prevented

32. Chapter 24 Evolution of species cont. • 2. Sympatric (“Same Country”) Speciation: Takes place in geographically overlapping populations • A reproductive barrier isolates a subset of a population without geographic separation from the parent species • Can result from polyploidy, natural selection, or sexual selection • Polyploidy: The presence of extra sets of chromosomes due to accidents during cell division • Autopolyploid: more than two chromosome sets, derived from one species • Allopolyploid: multiple sets of chromosomes derived from different species

33. Chapter 24 Evolution of species cont. • Punctuated equilibrium: periods of apparent stasis punctuated by sudden change • Gradual equilibrium: a change in a species’ existence that is relatively constant

34. Chapter 25 Earth History • Chemical and physical processes on early Earth may have produced very simple cells through a sequence of stages: 1. Abiotic synthesis of small organic molecules 2. Joining of these small molecules into macromolecules 3. Packaging of molecules into “protobionts” 4. Origin of self-replicating molecules • Earth formed about 4.6 billion years ago, along with the rest of the solar system

35. Chapter 25 Earth History cont. • Earth’s early atmosphere likely contained water vapor and chemicals released by volcanos: • N & NO2 • CO2 & CH3 • NH3 • H & HSO2 • Protobionts: aggregates of abiotically produced molecules surrounded by a membrane • Can replication and metabolize • maintain an internal chemical environment • could have formed spontaneously from abiotically produced organic compounds

36. Chapter 25 Earth History cont. • The first genetic material was probably RNA • RNA molecules called ribozymes have been found to catalyze many different reactions • Early protobionts with self-replicating, catalytic RNA would have been more effective at using resources and would have increased in number through natural selection • The early genetic material might have formed an “RNA world”

37. Chapter 25 Earth History cont. • Strata: layers of sedimentary rocks deposited into layers • richest source of fossils • fossil record reveals changes in the history of life on earth • reveal the relative ages of fossils • The fossil record is biased in favor of species that: • Existed for a long time • Were abundant and widespread • Had hard parts

38. Chapter 25 Earth History cont. • Radiometric dating: determining the absolute ages of fossils • A “parent” isotope decays to a “daughter” isotope at a constant rate • Each isotope has a known half-life, the time required for half the parent isotope to decay • The geologic record is divided into the: • Archaean eon (no life) • Proterozoic eon (1 celled and soft bodies) • Phanerozoic eon (fossil record)

39. Ceno- zoic Chapter 25 Earth History cont. Meso- zoic Humans Paleozoic Colonization of land Animals Origin of solar system and Earth 4 1 Proterozoic Archaean Prokaryotes years ago Billions of 3 2 Multicellular eukaryotes Single-celled eukaryotes Atmospheric oxygen

40. Chapter 25 Earth History cont. • Hypothesis of endosymbiosis: proposes that mitochondria and plastids (chloroplasts and related organelles) were formerly small prokaryotes living within larger host cells • Mitochondria evolved before plastids Endosymbiont: a cell that lives within a host cell • The prokaryotic ancestors of mitochondria and plastids probably gained entry to the host cell as undigested prey or internal parasites • In the process of becoming more interdependent, the host and endosymbionts would have become a single organism

41. Chapter 25 Earth History cont. • Evidence for endosymbiosis: • Similarities in inner membrane structures and functions • Division is similar in these organelles and some prokaryotes • These organelles transcribe and translate their own DNA • Their ribosomes are more similar to prokaryotic than eukaryotic ribosomes

42. Chapter 25 Earth History cont. • The history of life on Earth has seen the rise and fall of many groups of organisms as a result of: • Continental drift: • Oceanic and continental plates can collide, separate, or slide past each other • Interactions between plates cause the formation of mountains and islands, and earthquakes • Formation of the supercontinent Pangaea • The break-up of Pangaea lead to allopatric speciation • The current distribution of fossils reflects the movement of continental drift

43. Chapter 25 Earth History cont. 2. Mass extinctions • The fossil record shows that most species that have ever lived are now extinct • At times, the rate of extinction has increased dramatically and caused a mass extinction • In each of the five mass extinction events, more than 50% of Earth’s species became extinct • The presence of iridium in sedimentary rocks suggests a meteorite impact about 65 million years ago • The Chicxulub crater off the coast of Mexico is evidence of a meteorite that dates to the same time

44. Chapter 25 Earth History cont. 3. Adaptive radiations: evolution of diversely adapted species from a common ancestor upon introduction to new environmental opportunities • Mammals underwent an adaptive radiation after the extinction of terrestrial dinosaurs • The disappearance of dinosaurs (except birds) allowed for the expansion of mammals in diversity and size • Adaptive radiations can occur when organisms colonize new environments with little competition

45. Chapter 25 Earth History cont. • Homeotic genes determine such basic features as where wings and legs will develop on a bird or how a flower’s parts are arranged • Hox genes: class of homeotic genes that provide positional information during development • If they are expressed in the wrong location, body parts can be produced in the wrong location • For example, in crustaceans, a swimming appendage can be produced instead of a feeding appendage

46. Chapter 25 Earth History cont. • Evolution is like tinkering—it is a process in which new forms arise by the slight modification of existing forms • Natural selection can only improve a structure in the context of its current utility

47. Chapter 26 Phylogeny and the Tree of Life • Phylogeny: the evolutionary history of a species or group of related species • Systematics: classifies organisms and determines their evolutionary relationships • use fossil, molecular, and genetic data to infer evolutionary relationships • Taxonomy: the ordered division and naming of organisms • Binomial: two-part scientific name of a species • The first part of the name is the genus • The second part, called the specific epithet, is unique for each species within the genus

48. Chapter 26 Phylogeny and the Tree of Life • The taxonomic groups from broad to narrow are domain, kingdom, phylum, class, order, family, genus, and species • A taxonomic unit at any level of hierarchy is called a taxon • Systematists depict evolutionary relationships in branching phylogenetic trees • show patterns of descent

49. Chapter 26 Phylogeny and the Tree of Life • Phylogenetic trees do show patterns of descent • Phylogenetic trees do not indicate when species evolved or how much genetic change occurred in a lineage

50. Types of Speciation Allopatric Speciation Barriers may be: Behavioral Temporal Geographical Physiological Sympatric Speciation