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SES versus CABG for unprotected left main stenosis

SES versus CABG for unprotected left main stenosis. Objective To compare SES and CABG in patients with uLMCA stenosis. Study: Multi center, randomized, non inferiority trial.

cedric-grimes
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SES versus CABG for unprotected left main stenosis

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  1. SES versus CABG for unprotected left main stenosis Objective To compare SES and CABG in patients with uLMCAstenosis. Study: Multi center, randomized, non inferiority trial. Population: Symptomatic patients with an isolated ULM ostialmidshaft or bifurcation stenosis. Consensus between surgeon and cardiologist on eligibility. Endpoint: Noninferiority in freedom from MACE (composite of cardiac death, MI, TVR) at f-up.

  2. SES versus CABG for unprotected left main stenosis PCI n=100 Randomized n=201 CABG n=101

  3. SES versus CABG for unprotected left main stenosis Event rate at a 12 months f-up (%) P=0.19 P<0.001 P=0.002 P=0.35 P valuesfornon-inferiority

  4. SES versus CABG for unprotected left main stenosis Conclusion: In patients with ULM stenosis, DES implantation is inferior to CABG at 12 months f-up, mainly driven by repeat revascularizations. For hard points PCI results are favourable. Freedom from angina was similar between groups. Stroke was not in primary end-point. Boudriot et al. J Am Col Cardiol 2011;57:538-545

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