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ELEVATION AND PACHYMETRY VALUES IN NORMAL CORNEAS OBTAINED BY GALILEI

ELEVATION AND PACHYMETRY VALUES IN NORMAL CORNEAS OBTAINED BY GALILEI. Claudia Blanco Marín MD. Maria Ximena Núñez MD. Vision Sana Research Group Cornea and Refractive Surgery Unit Clinica de Oftalmologia de Cali Cali-Colombia. ASCRS Boston April 9 -14 2010.

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ELEVATION AND PACHYMETRY VALUES IN NORMAL CORNEAS OBTAINED BY GALILEI

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  1. ELEVATION AND PACHYMETRY VALUES IN NORMAL CORNEAS OBTAINED BY GALILEI Claudia Blanco Marín MD. Maria Ximena Núñez MD. Vision Sana Research Group Cornea and Refractive Surgery Unit Clinica de Oftalmologia de Cali Cali-Colombia ASCRS Boston April 9 -14 2010 Theauthorshave no financialinterest in thesubjectmatter of this poster.

  2. PURPOSE To obtain the topographic parameters in normal corneas of candidates for refractive surgery with the Galilei dual-Scheimpflug analyzerand compare them with the Orbscan II scanning-slit system.

  3. METHODS • Prospective study • Two measurements per eye from each patient and each device were taken by the same operator. • To obtain equal conditions in elevation measurements, the Orbscan II best fit sphere (BFS ) was obtained from an 8-mm-diameter area like the Galilei system does. • This study was analyzed with descriptive statistics and an univariate analysis of variables (Galilei and Orbscan) was performed in order to calculate: - The central tendency (mean , median) and confidence interval (CI) -The distribution (normal distribution test: Kolmogorov-Smirnov test) -The dispersion (Standard Deviation, SD) • To evaluate the differences in means between the two groups of gathered data (Galilei and Orbscan II) the t-test (parametric test) was used , with a level of significance of p<0.005.

  4. SUBJECTS • 92 eyes were examined with the two devices. • Gender : 25 males / 67 females • Ages 17 to 55 years old, mean: 32,77 years old (95% CI 30,57 - 34,96) • DX: Myopia 23% Myopic astigmatism 53,2% Hyperopia11% Hyperopic astigmatism 7,5% Presbyopia3,3 % Mixed astigmatism 2 % • We excluded keratoconus and any keratoconus suspects identified with the CLMI index from the Keratron Scout and the KPI from the Galilei .

  5. RESULTS Anterior Best-fit Sphere Radii (raBFS) The mean radius of the anterior best-fit sphere (raBFS) was: 7.84 +/- 0.23 mm (SD) (95% CI 7,795 -7,891) with the Galilei 7.84 +/- 0.23 mm (SD) (95% CI 7,791 -7,890) with the Orbscan II p= 1,0

  6. RESULTS Posterior Best-fit Sphere Radii (rpBFS) The mean radius of the posterior best-fit sphere (rpBFS) was: 6.50 +/- 0.20 mm(SD) (95% CI 6,46 -6,54) with the Galilei 6.46 +/- 0.20 mm (SD) (95% CI 6,41 -6,50) with the Orbscan II p=0,17.

  7. RESULTS Radius of the Maximum Anterior Elevation (rMAE) Sample size =92 Lowest value =1,5 Highest value = 12 Mean = 5,61 SD = 2,19 Sample size = 92 Lowest value = 2 Highest value = 14 Mean = 4,64 SD = 2,23 The mean radius of the maximum anterior elevation (rMEA) was : 5,61 +/- 2,19 µm(SD) (95% CI 5,16 – 6,07 ) with the Galilei 4,64 +/- 2,23µm (SD), (95% CI 4,18 – 5,11) with the Orbscan II p= 0,0023

  8. RESULTS Radius of the Maximum Posterior Elevation (rMPE) Sample size = 92 Lowest value = 5,50 Highest value = 22,00 Mean = 13,00 SD = 3,35 • The mean radius of the maximum posterior elevation (rMPE) was: • 13,0 +/- 3,35 µm (SD) • (95% CI 12,31 – 13,69) • with the Galilei • 13,84 +/- 6,65 µm (SD), • (95% CI 12,47 – 15,22) • with the Orbscan II • p= 0,321 Sample size = 92 Lowest value = 1,00 Highest value = 32,00 Mean = 13,84 SD= 6,65

  9. RESULTSCentral Corneal Thickness (CCT) • The Central Corneal Thickness (CCT) mean was: • 549 +/- 29.96 microns (SD) • (95% CI 542 – 555) • with the Galilei, • Lowest 474 highest 612 • 551 +/- 38.52 microns(SD) • (95% CI 543 – 559) • with the OrbscanII • Lowest 459 highest 644 • p=0,722

  10. RESULTS Corneal Thinnest Point CTP Corneal Thinnest Point mean CTP was : 546 +/- 29.6 microns(SD) (95% CI 540 – 552) with the Galilei Lowest 472 highest 611 543 +/- 37.8 microns (SD) (95% CI 535 –551) with the Orbscan II p=0,59.

  11. Conclusion: There were a statistical difference between the two devices in the maximun anterior elevation with a better normal tendency of the measurements in the Galilei results. The pachymetry analysis shows a higher dispersion of the data for the Orbscan II ; due to a SD of 38.52 microns(µ) for the Orbscan II and 29.96 µ for the Galilei in the CCT and 37.8 µ for the Orbscan II and 29.6 µ for the Galilei in the CTP.

  12. Conclusion: Even though both devices have different centering systems, most of the elevation and pachymetry mean results did not show significant differences. It is important to know the elevation and pachymetry variables in normal corneas, and their distribution to establish the clinical cut off with the Galilei dual-scheimpflug analyzer.

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