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Quality Assessment for Routine Clinical MR Spectroscopy

Quality Assessment for Routine Clinical MR Spectroscopy. Diana M. Lindquist, PhD Assistant Professor of Radiology. Purpose. Clinical indication: apparently abnormal metabolite ratios in infant with normal imaging findings.

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Quality Assessment for Routine Clinical MR Spectroscopy

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  1. Quality Assessment for Routine Clinical MR Spectroscopy Diana M. Lindquist, PhD Assistant Professor of Radiology

  2. Purpose • Clinical indication: apparently abnormal metabolite ratios in infant with normal imaging findings. • Quality control is as important in clinical spectroscopy as in research • Develop a simple short protocol for quality control in clinical MRS • Localization • Spectral data

  3. Methods • Standard head coil and manufacturer’s phantom • Protocol • Axial localizer • 3 voxels (8 cm3) • PRESS • Total time: 30 minutes

  4. Results: Image Uniformity

  5. Results: Voxel Localization • Mean voxel size was 20.2 (± 0.8) by 18.9 (± 0.4) mm2 in-plane • One voxel is adequate; scan time reduced from 30 to 15 minutes

  6. Sample spectra NAA Cr Cho Lac TE 35 ms TE 144 ms

  7. Results: Metabolite Ratios

  8. Conclusions • Following implementation of this protocol, we are now able to detect and correct scanner instabilities. • QC data are useful as a monitor of system performance • Scheduling still difficult even with a 15 minute exam.

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