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ECZEMA & DERMATITIS. Definition:. Erythema. سير نکس مکرر از صفحه مزمن به صفحه حاد. صفحه A C U T E. Papula و اذيما. سير بدون آب زدن. صفحه C H R O N I C. تحول صفحه تحت الحاد به حاد. Vesicula. Lichenification. Weeping ، توليد ارچق و بعضاً Pustula. Scaling
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ECZEMA & DERMATITIS Definition:
Erythema سير نکس مکرر از صفحه مزمن به صفحه حاد صفحه A C U T E Papula و اذيما سير بدون آب زدن صفحه C H R O N I C تحول صفحه تحت الحاد به حاد Vesicula Lichenification Weeping، توليد ارچق و بعضاً Pustula Scaling يا توليد تفلس واحمرار صفحه Sub acute سير بنفسهی به صفحه مزمن نورمال شدن جلد بدون scar
Acute eczema The epidermis shows distinictvesicule formation
Chronic eczema hyperkeratosis,some patchy parakeratosis.irregularacanthosis. And lymphocytic infiltration in the upper dermis
Sub acute eczema Irriguleracanthosis, patchy spongiosis
Etiology: Predisposition (Genetic) • Irritants. (physical + chemical) • Sensitizers (plants, cosmetics, occupational etc.) • External infections. (strepto - staphylococci , fungus) • Emotional (Strains, stress) • Diet • Diathesis (Xerodermic, allergic, Seborrhoeic, etc) • Climate (temperature and humidity).
Classification and clinical forms: • Exogenous Eczemas: • Allergic contact dermatites • Irritant dermatitis • Allergic photocontact dermatitis • dermatophytide B. Endogenous Eczemas: • Atopic Dermatitis or Atopic Eczema (AD) • Seborrhoeic dermatitis (SD) • NumularEczcma Discoid Eczema. • Pompholyx • Pityriasis alba. • Absorption, varicose, perioral dermatitis and non- classified eczema.
Atopic dermatitis Pathogenesis &Immunology
Eczema Vaccinatum Eczema Herpaticum
Clinical feature * Phases: • Infantile stage: 2 months up to 2 years old • Childhood type: 2 years up to 12 years old Adult type: 12 years up to 23 years old Infantile AD Childhood AD Adulthood AD
AD در مرحله آب زدن مترافق با ارچق Acute AD در دوره infancy AD مزمن مترافق با lichenification
Atopic Dermatitis (Adulthood) In flexure areas Denniemorgan’s sign
Seborrhoeic dermatitis (SD) Etiology and pathogenesis
Clinical features SD Capitis (adult) SD Facial (adult)
Seborrhoeic Dermatitis SD Capitis (infant) Leiners Disease
Infective dermatitis Infective eczema Infected eczema
acute erythematous,papulo vesicular eruptionextremlypruritic
Contact dermatitis (Contact eczema) • Irritant Contact Dermatitis(ICD)
managment • Avoid contact with allergens and irritants • Use of gloves • Use of topical moderate and potent corticosteroids • Systemic steroids for 3weeks. Allergic contact dermatitis
Clinical feature • Subacute and chronic • Occurs in men more than women • Number of plaqes:2,3 • Involvment sites: dorsal side of hand, forearm,trunk, lower limbs. • Yellow crust
managment • Emolients • Topical steroids • In exudative cases: oral antibiotic
Pompholyx &dyshidrosis • Bilateral Relapsing pruritic , deep vesicules with 1-5mm size in palms and planter area. • 20-25% hand eczema • Age:20-40y
Treatment • Soak • Prednisolon:1m/kg • Tacrolimus with topical steroids for 3-4weeks. • Oral antihistamine • flucloxacillin
Pityriasis alba • Decrease the number of active melanocytes with decrease in number and size of melanosoms. Facial P. Alba (Common )
Usually 4 plaqes or more(0.5-2cm) • More in summer • Duration:months and sometimes years • Emolients • Topical Hydrocortison1% Generalisedp.a(rare)
Lichen simplex chronicus or circumscribed neurodermatitis Etiology &pathogenesis
Clinical feature Lichenoid papules lichen simplex chronicus
Clinical feature • Lichen nuchae • Pruritusani • Pruritus vulva • Pruritusscroti
photodermatitis • Photo toxic eczema • Photo allergic eczema
phototoxic dermatitis phototoxic dermatitis
Phytophotodermatitis PhytophotodermatitisHyperpigmentation Phytophotodermatitis (Plant + Light)
Usually exposed area • Papulo vesicular lesions • Odema • Weeping • Crust • pruritus allergic photodermatitis