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Osteoscoop - Issue N°273 – February 2013

Regulation of beta catenin signaling and parathyroid hormone anabolic effects in bone by the matricellular protein periostin. Osteoscoop - Issue N°273 – February 2013. +PTH. Increased Cortical bone mineral density. Postn +/+. Preosteoblast. +PTH. Osteoblasts.

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Osteoscoop - Issue N°273 – February 2013

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  1. Regulation of beta catenin signaling and parathyroid hormone anabolic effects in bone by the matricellular protein periostin Osteoscoop - Issue N°273 – February 2013

  2. +PTH Increased Cortical bone mineral density Postn+/+ Preosteoblast +PTH Osteoblasts Decreased Cortical bone mineral density Postn-/- Preosteoblast Osteoblasts

  3. +PTH Increased Cortical bone mineral density Postn+/+ Preosteoblast +PTH Osteoblasts Decreased Cortical bone mineral density Postn-/- Preosteoblast Osteoblasts PTH Wnt P P P LRP5/6 b-Catenin b-Catenin Sost Postn POSTN Nucleus

  4. +PTH Increased Cortical bone mineral density Postn+/+ Preosteoblast +PTH Osteoblasts Decreased Cortical bone mineral density Postn-/- Preosteoblast Osteoblasts Wnt PTH IntegrinaVb3 P P P LRP5/6 b-Catenin b-Catenin Sost SOST Postn POSTN Nucleus

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