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Eukaryotic Genome & Gene Expression. Genome Structure and Postranscriptional Events. Pre-mRNA. Splicing Polyadenylation Capping. AAAAAAA 250. pppGp. mRNA. Eukaryotic Transcription & Translation are Compartmentalized. Categories of Genes and Non-Coding Sequences. Class I genes
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Genome Structure and Postranscriptional Events Pre-mRNA Splicing PolyadenylationCapping AAAAAAA250 pppGp mRNA
Eukaryotic Transcription & Translation are Compartmentalized
Categories of Genes and Non-Coding Sequences Class I genes rDNA encodes rRNA Moderately repetitive sequences Transcribed by RNA polymerase I Class II genes mRNA (protein encoding) and snRNA Unique sequences Transcribed by RNA polymerase II Class III genes tRNA, 5S rRNA, U6 snRNA Moderately repetitive sequences Transcribed by RNA polymerase III Non-coding regions Repetitive elements Transposable elements (some transcribed) Pseudogenes
Alternative Splicing Results in Different mRNAs and Proteins