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COLPOSCOPY RANDOM CERVICAL BIOPSIES ENDOCERVICAL CURETTAGE

COLPOSCOPY RANDOM CERVICAL BIOPSIES ENDOCERVICAL CURETTAGE. Robert.G.Pretorius@kp.org S.C.P.M.G.-Fontana. I. IV. II. III.

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COLPOSCOPY RANDOM CERVICAL BIOPSIES ENDOCERVICAL CURETTAGE

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  1. COLPOSCOPYRANDOM CERVICAL BIOPSIESENDOCERVICAL CURETTAGE Robert.G.Pretorius@kp.org S.C.P.M.G.-Fontana

  2. I IV II III

  3. PROPORTION OF CIN 3 OR CANCER (CIN 3+) DIAGNOSED BY COLPOSCOPICALLY DIRECTED BIOPSY OF A VISIBLE LESION, ‘RANDOM’ BIOPSY FROM A CERVICAL QUADRANT WITHOUT A LESION, OR SOLELY BY ECC OF CIN 3+ Pretorius RG et. al. JLGTD 2011;15:180-8

  4. SENSITIVITY FOR CIN 3 OR CANCER (CIN 3+) OF BIOPSY OF CERVICAL QUADRANTS WITH COLPOSCOPIC IMPRESSION OF HPV, CIN, OR CANCER AS A FUNCTION OF THE NUMBER OF CERVICAL QUADRANTS WITH CIN 3+ (0 quadrants is diagnosis solely by positive ECC) 1p for trend <.001 from Pretorius RG et. al. JLGTD 2011;15:180-8

  5. AVERAGE EPITHELIAL THICKNESS (MICRONS) BY COLPOSCOPIC IMPRESSION AND HISTOLOGY (SELECTED REVIEW OF SPOCCS I SLIDES) Yang B et. al. Gynecol Oncol 2008;110:32-6

  6. YIELD OF CIN 3 OR CANCER PER COLPOSCOPY Pretorius RG et. al. JLGTD 2011;15:180-8

  7. COMPARISON OF CHINA COLPOSCOPY CLINIC (in which eligible women were 35 to 50 years of age, had colposcopy for cytology of Cancer, HSIL, AGUS, LSIL, or ASC-US with positive HR-HPV and were diagnosed with CIN 3+ only by cervical biopsy and/or ECC showing CIN 3+) WITH A SIMILAR MATCHED SERIES FROM S.C.P.M.G.-FONTANA 2007-2009 122.7% vs. 23.1%, p=.95, 210.8% vs. 8.5%, p=.57, Pretorius RG et. al. JLGTD2012;16:333-8

  8. PROPORTION OF CIN 3 OR CANCER (CIN 3+) IN S.C.P.M.G.-FONTANA COLPOSCOPY CLINIC 2007-2009 DIAGNOSED SOLELY BY ECC of CIN 2+ Pretorius RG et. al. JLGTD 2012;16:333-8

  9. ‘RANDOM’ BIOPSIES IN CERVICAL QUADRANTS WITHOUT VISIBLE LESIONS AND ECC SHOULD BE DONE AT COLPOSCOPY FOR EVALUATION OF ABNORMAL CERVICAL CANCER SCREENING TESTSTHE ECC MAY BE OMITTED ON WOMEN UNDER AGE 25 YEARS Pretorius RG et. al. JLGTD 2012;16:333-8

  10. Robert.G.Pretorius@kp.org THANK YOU FOR YOUR ATTENTION

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