Silagra Tablets (Generic Sildenafil Citrate Tablets by Cipla)

1. Silagra Tablets (Generic Sildenafil Citrate Tablets by Cipla) © Clearsky Pharmacy ( www.clearskypharmacy.biz )

2. Silagra Tablets (Generic Sildenafil Citrate Tablets by Cipla) Silagra Tablets (Generic Sildenafil Citrate Tablets by Cipla) is a phosphodiesterase-5 (PDE5) inhibitor which is used to treat adult men with erectile dysfunction, which is the inability to achieve or maintain a penile erection sufficient for satisfactory sexual performance. Silagra restores impaired erectile function by increasing blood flow to the penis in the presence of sexual stimulation. © Clearsky Pharmacy ( www.clearskypharmacy.biz )

3. Silagra Tablets (Generic Sildenafil Citrate Tablets by Cipla) Active Ingredient The active ingredient contained in Silagra tablets is Sildenafil Citrate. Each Silagra tablet contains 100 mg of the active ingredient Sildenafil Citrate. © Clearsky Pharmacy ( www.clearskypharmacy.biz )

4. Silagra Tablets (Generic Sildenafil Citrate Tablets by Cipla) Chemical Structure The structure of Sildenafil Citrate is given below: © Clearsky Pharmacy ( www.clearskypharmacy.biz )

5. Silagra Tablets (Generic Sildenafil Citrate Tablets by Cipla) Silagra Tablets are manufactured by Cipla Limited, India in the strength of 100 mg. (Website: https://www.cipla.com/ https://www.cipla.com/ ) URL: URL: https://www.clearskypharmacy.biz/sildenafil-silagra-by-cipla.html https://www.clearskypharmacy.biz/sildenafil-silagra-by-cipla.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

6. Silagra Tablets (Generic Sildenafil Citrate Tablets by Cipla) Sildenafil Citrate Tablets – Brand Names Sildenafil Citrate tablets are available as Silagra, Alphagra, Lovegra (Special formulation for women), Suhagra, Viagra, Kamagra, Kamagra chewable, Caverta, Penegra, Cenforce, Erix, Ceverta, Androz and Alsigra. URL: URL: https://www.clearskypharmacy.biz/sildenafil-silagra-by-cipla.html https://www.clearskypharmacy.biz/sildenafil-silagra-by-cipla.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

7. Silagra Tablets (Generic Sildenafil Citrate Tablets by Cipla) Uses of Silagra 100mg Tablets Silagra (Generic Sildenafil Citrate Tablets by Cipla) is used to treat men who have erectile dysfunction (also called sexual impotence). Sildenafil belongs to a group of medicines called phosphodiesterase 5 (PDE5) inhibitors. These medicines prevent an enzyme called phosphodiesterase type-5 from working too quickly. Erectile dysfunction is a condition where the penis does not harden and expand when a man is sexually excited, or when he cannot keep an erection. When a man is sexually stimulated, his body's normal response is to increase blood flow to his penis to produce an erection. By controlling the enzyme, Sildenafil helps to maintain an erection after the penis is stroked. Without physical action to the penis, such as that occurring during sexual intercourse, Sildenafil will not work to cause an erection. URL: URL: https://www.clearskypharmacy.biz/sildenafil-silagra-by-cipla.html https://www.clearskypharmacy.biz/sildenafil-silagra-by-cipla.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

8. Silagra Tablets (Generic Sildenafil Citrate Tablets by Cipla) Uses of Silagra 100mg Tablets Sildenafil is also used in both men and women to treat the symptoms of pulmonary arterial hypertension (WHO Group I) to improve exercise ability. This is a type of high blood pressure that occurs between the heart and the lungs. When hypertension occurs in the lungs, the heart must work harder to pump enough blood through the lungs. Sildenafil works on the PDE5 enzyme in the lungs to relax the blood vessels. This will increase the supply of blood to the lungs and reduce the workload of the heart. URL: URL: https://www.clearskypharmacy.biz/sildenafil-silagra-by-cipla.html https://www.clearskypharmacy.biz/sildenafil-silagra-by-cipla.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

9. Silagra Tablets (Generic Sildenafil Citrate Tablets by Cipla) Silagra Tablets Dosage The recommended starting dose of Silagra Tablets Sildenafil Citrate Tablets by Cipla) is 50 mg taken approximately one hour before sexual activity. Based on efficacy and toleration, the dose may be increased to 100 mg or decreased to 25 mg. The maximum recommended dose is 100 mg. The maximum recommended dosing frequency is once per The maximum recommended dosing frequency is once per day. day. If Sildenafil is taken with food, the onset of activity may be delayed compared to the fasted state. Silagra Tablets (Generic URL: URL: https://www.clearskypharmacy.biz/sildenafil-silagra-by-cipla.html https://www.clearskypharmacy.biz/sildenafil-silagra-by-cipla.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

10. Silagra Tablets (Generic Sildenafil Citrate Tablets by Cipla) Silagra Tablets Contraindications Silagra tablets are contraindicated in patients with a hypersensitivity to Sildenafil Citrate or any other component of this medicine. Administration of Silagra tablets to patients using nitric oxide donors, such as organic nitrates or organic nitrites in any form is contraindicated as Sildenafil Citrate is known to potentiate the hypotensive effect of nitrates. Administration of Generic Sildenafil Citrate when undergoing therapy with Guanylate Cyclase (GC) stimulators, such as Riociguat is also contraindicated as it may potentially lead to symptomatic hypotension. URL: URL: https://www.clearskypharmacy.biz/sildenafil-silagra-by-cipla.html https://www.clearskypharmacy.biz/sildenafil-silagra-by-cipla.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

11. Silagra Tablets (Generic Sildenafil Citrate Tablets by Cipla) Silagra Tablets Contraindications Sildenafil is contraindicated in men for whom sexual intercourse is inadvisable due to cardiovascular risk factors (e.g. patients with severe cardiovascular disease such as established cardiac failure and unstable angina pectoris). The safety of Sildenafil Citrate (Silagra Tablets) has not been studied in the following sub-groups of patients and its use is herefore contraindicated until further information is available: severe hepatic impairment, hypotension (blood pressure <90/50 mmHg), hypertension (blood pressure >170/110 mmHg), recent history of stroke or myocardial infarction and known hereditary degenerative retinal disorders such as retinitis pigmentosa. URL: URL: https://www.clearskypharmacy.biz/sildenafil-silagra-by-cipla.html https://www.clearskypharmacy.biz/sildenafil-silagra-by-cipla.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

12. Silagra Tablets (Generic Sildenafil Citrate Tablets by Cipla) Storage Instructions Silagra Tablets (Generic Sildenafil Citrate Tablets by Cipla) have to be stored at controlled room temperature i.e. from 20°C to 25°C (68°F to 77°F) with excursions permitted between 15° to 30°C (59° to 86°F). Keep this as well as all other medicines away from children and pets. URL: URL: https://www.clearskypharmacy.biz/sildenafil-silagra-by-cipla.html https://www.clearskypharmacy.biz/sildenafil-silagra-by-cipla.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

13. Silagra Tablets (Generic Sildenafil Citrate Tablets by Cipla) Warnings Patients must not use Silagra (Generic Sildenafil Citrate Tablets) in case sexual activity is not advisable due to their cardiovascular status. Patients must stop taking Silagra tablets and seek immediate medical care in case a sudden loss of vision occurs in one or both eyes, which could be a sign of non arteritic anterior ischemic optic neuropathy (NAION). Sildenafil Citrate tablets must be used with caution, and only in cases when the anticipated benefits outweigh the risks, in patients with a history of NAION. Patients with a "crowded" optic disc can also be at an increased risk of NAION. URL: URL: https://www.clearskypharmacy.biz/sildenafil-silagra-by-cipla.html https://www.clearskypharmacy.biz/sildenafil-silagra-by-cipla.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

14. Silagra Tablets (Generic Sildenafil Citrate Tablets by Cipla) Warnings Use Silagra with caution in patients with anatomical deformation of the penis (e.g., angulation, cavernosal fibrosis, or Peyronie's disease) or in patients who have conditions, which may predispose them to priapism (e.g., sickle cell anemia, multiple myeloma, or leukemia). In the event of an erection that lasts longer than 4 hours, the patient should seek immediate medical treatment. In case priapism (painful erection greater than 6 hours in duration) is not treated immediately, penile tissue damage and permanent loss of potency could occur. URL: URL: https://www.clearskypharmacy.biz/sildenafil-silagra-by-cipla.html https://www.clearskypharmacy.biz/sildenafil-silagra-by-cipla.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

15. Silagra Tablets (Generic Sildenafil Citrate Tablets by Cipla) Warnings Patients should stop using Silagra (Generic Sildenafil Citrate Tablets) and seek immediate medical attention in the case of sudden decrease or loss of hearing. Caution is advised when Generic Sildenafil Citrate tablets are co- administered along with alpha-blockers or anti-hypertensives. Using both the medicines at the same time can lead to hypotension. Decreased blood pressure, syncope, and prolonged erection can take place at higher Sildenafil Citrate exposures. In patients taking strong CYP inhibitors, such as Ritonavir, Sildenafil exposure is increased. Decrease in Silagra dosage is recommended. URL: URL: https://www.clearskypharmacy.biz/sildenafil-silagra-by-cipla.html https://www.clearskypharmacy.biz/sildenafil-silagra-by-cipla.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

16. Silagra Tablets (Generic Sildenafil Citrate Tablets by Cipla) Driving and Operating Machines Sildenafil Citrate (Silagra Tablets) has moderate influence on the ability to drive and use machines. As dizziness and altered vision were reported in clinical trials with Sildenafil Citrate tablets, patients should be aware of how they might be affected by Silagra, before driving or using machines. URL: URL: https://www.clearskypharmacy.biz/sildenafil-silagra-by-cipla.html https://www.clearskypharmacy.biz/sildenafil-silagra-by-cipla.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

17. Silagra Tablets (Generic Sildenafil Citrate Tablets by Cipla) Side Effects Side effects of Silagra (Generic Sildenafil Citrate Tablets) can include headache, dizziness, flushing, indigestion, nasal congestion, diarrhoea and rash. Tell your doctor as soon as possible in case you notice any of the following symptoms: unusual heart beat, urinary tract infection, blood in the urine, changes in vision such as blurring, a blue colour to your vision or a greater awareness of light, persistent headache or fainting and bleeding from the nose. Seek prompt medical treatment in case of the following rare Generic Sildenafil Citrate side effects such as signs of allergy (shortness of breath, wheezing or difficulty breathing; swelling of the face, lips, tongue or other parts), chest pain, sudden decrease or loss of hearing, seizures, fits or convulsions are observed. URL: URL: https://www.clearskypharmacy.biz/sildenafil-silagra-by-cipla.html https://www.clearskypharmacy.biz/sildenafil-silagra-by-cipla.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

18. Silagra Tablets (Generic Sildenafil Citrate Tablets by Cipla) Silagra Overdose In studies conducted with healthy volunteers of single doses of Sildenafil Citrate (Silagra tablets) up to 800 mg, adverse reactions were similar to those observed at lower doses but incidence rates and severities were increased. URL: URL: https://www.clearskypharmacy.biz/sildenafil-silagra-by-cipla.html https://www.clearskypharmacy.biz/sildenafil-silagra-by-cipla.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

19. Silagra Tablets (Generic Sildenafil Citrate Tablets by Cipla) Treatment of Silagra Overdose In cases of overdose of Silagra (Generic Sildenafil Citrate Tablets), standard supportive measures must be used as necessary. Renal dialysis is not expected to accelerate clearance as Sildenafil Citrate is highly bound to plasma proteins and it is not eliminated in the urine. URL: URL: https://www.clearskypharmacy.biz/sildenafil-silagra-by-cipla.html https://www.clearskypharmacy.biz/sildenafil-silagra-by-cipla.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

20. Silagra Tablets (Generic Sildenafil Citrate Tablets by Cipla) Silagra Tablets During Pregnancy Sildenafil Citrate (Silagra tablets) has been classified by the US FDA as Pregnancy Category B. There are no adequate and well-controlled studies conducted of Sildenafil Citrate in pregnant women. Silagra is not indicated for use in women. Animal reproduction studies conducted with sildenafil did not show adverse developmental outcomes when administered during organogenesis in rats and rabbits at oral doses up to 16 and 32 times, respectively, the maximum recommended human dose (MRHD) of 100 mg/day on a mg/m 2 basis. URL: URL: https://www.clearskypharmacy.biz/sildenafil-silagra-by-cipla.html https://www.clearskypharmacy.biz/sildenafil-silagra-by-cipla.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )

21. Silagra Tablets (Generic Sildenafil Citrate Tablets by Cipla) Silagra Tablets Silagra Tablets (Generic Sildenafil Citrate Tablets) manufactured by Cipla Limited, India. URL: URL: https://www.clearskypharmacy.biz/sildenafil-silagra-by-cipla.html https://www.clearskypharmacy.biz/sildenafil-silagra-by-cipla.html © Clearsky Pharmacy ( www.clearskypharmacy.biz )