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Biological Physics: Understanding the Physics of Biological Systems

Biological Physics: Understanding the Physics of Biological Systems Ido Braslavsky, Peter Jung, Alexander B. Neiman, and David F. J. Tees Dept. of Physics & Astronomy, Ohio University, Athens, OH 45701. Cell Adhesion Biophysics. Computational Neuroscience.

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Biological Physics: Understanding the Physics of Biological Systems

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  1. Biological Physics: Understanding the Physics of Biological Systems Ido Braslavsky, Peter Jung, Alexander B. Neiman, and David F. J. Tees Dept. of Physics & Astronomy, Ohio University, Athens, OH 45701 Cell Adhesion Biophysics Computational Neuroscience • How can we prevent heart disease and cancer? • How can arthritis best be treated? • How can drugs be targeted better so that we can use smaller doses? • How can we detect low concentrations of viruses and bacteria for disease diagnosis and homeland security? Peter Tass • How do sharks find prey? • How does memory work? • What do logjams have to do with Lou Gehrig’s disease? • What is going wrong in Parkinson’s Disease and epilepsy? H. L. Goldsmith Antifreeze Proteins and DNA Sequencing Ido Braslavsky • How can we preserve organs better? • How can some fish and insects survive freezing temperatures? • Can single molecule DNA sequencing produce the immense amount of sequence information needed to defeat cancer? Lon Wilkens H. L. Goldsmith Norbert Wu Guntheroth, W. G. et al. J. Appl. Physiol. 53:510, 1982. H. L. Goldsmith www.le.ac.uk/by/je14/integrin5.htm Collaborations and outreach Local: Active collaborations with Ohio University Departments of Chemistry & Biochemistry, Chemical Engineering and Biological Sciences External: Active collaborations with researchers at Ohio State University, University of California (San Diego), University of California (Irvine), Research Center Jülich (Germany), Queen’s University (Canada), Yale University. Vladimir Parpura D.F.J. Tees Alberts et al, Molecular Biology of the Cell, 2002 Journal of Cell Biology 164:887 2004 Anthony Brown Ido Braslavsky Education and Training Funding Anthony Brown • Specialty courses offered: • Cell and Molecular Biophysics (PHYS 461) • Biophysics Journal Club • Experimental Neurophysiology and Computational Neuroscience labs. • Undergrad and grad student projects National Institutes of Health National Science Foundation American Heart Association Biotech corporate funding M. J. Schnitzer, Nature 410:878, 2001 Visscher, Schnitzer & Block, Nature, 400:184, 1999 Background: Topoisomerase on DNA (www.mb.tn.tudelft.nl/image_gallery/big/dnatopo_big.jpg)

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