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Research Studies on Various Medical Topics

Explore a range of research studies conducted at The Aga Khan University, Pakistan, on topics such as enteric fever prevention, dental stem cells, cancer, leukemia, tuberculosis, and arboviruses.

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Research Studies on Various Medical Topics

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  1. Bench Space Dashboard Juma Lab (Ground Floor) Updated on 19th Feb 2019

  2. Bench no. A-5 SEAP II The Project is a prospective study aiming to generate data to inform policy recommendations on enteric fever prevention and control, as well as to facilitate typhoid vaccine implementation Aug 2016 – Sep 2018 ext. Sep 2019 Dr. Farah Qamar Associate Professor Paediatrics & Child Health. The Aga Khan University, Pakistan Core Equipment Grant Equipment

  3. Bench no. A-6 Intussusception Study A self controlled Case Series Study, based on Intussusception Monitoring in infants after Introduction of Oral Rotavirus Vaccine: Self-Controlled Case-Series in Pakistan hospitals. Aug 2017 – Oct 2019 Dr. S. Asad Ali Associate Professor Pediatrics & Child Health. The Aga Khan University, Pakistan Core Equipment Grant Equipment

  4. Bench no. A-8 Dr. S. Asad Ali Associate Professor Pediatrics & Child Health. The Aga Khan University, Pakistan Rotavirus vaccine Impact Assessment of Rotavirus Vaccine Introduction in Pakistan’s Routine Immunization Program. Aug 2018-Jun 2020 Core Equipment Grant Equipment

  5. Bench no. A-9 DENTAL STEM CELLS This study is about Human Dental Pulp Stem Cells of Permanent Teeth (DPSC) & Stem Cells from Exfoliated Deciduous Teeth (SHED): A Comparison of Dental Tissue Regeneration April 2015 – ext. Dec 2020 Dr. Tashfeen Ahmed Assistant Professor Department of Surgery. The Aga Khan University, Pakistan Core Equipment

  6. Bench no. A-10 Dr. Shahid Pervez Professor Pathology & Lab Medicine. The Aga Khan University, Pakistan • EFGR Signalling Pathway Analysis: • in Oral Squamous Cell Carcinoma Dec 2015 – Sep 2020 Core Equipment

  7. Bench no. A-12 Dr. Sohail Awan Associate Professor Department of Surgery. The Aga Khan University, Pakistan Genetic Mutations Causing Hearing Loss in the Families of Sindh and Baluchistan March 2018 – March 2020 Core Equipment

  8. Bench no. A-13 Dr. Kulsoom Ghias Associate Professor Biological & Biomedical Sciences. The Aga Khan University, Pakistan . Head & Neck Cancer This study will be characterizing role of neutrophils in progression of head and neck squamous cell carcinoma Jun 2018– Dec 2020 Core Equipment

  9. Bench no. A-14 Dr. Fareena Bilwani Assistant Professor Biological & Biomedical Sciences. The Aga Khan University, Pakistan Acute Myeloid Leukemia This study will be characterizing determinants of acute myeloid leukemia resistance to ex-vivo expanded allogeneic natural cell-mediated killing May 2017 – May 2021 Core Equipment

  10. Bench no. A-15 Dr. Najeeha Iqbal Assistant Professor Paediatrics & Child Health. The Aga Khan University, Pakistan Exploration of TB Biomarkers in Pakistani Children. • MiEED • This Study covers the aspect of Microbiota, Inflammation & Environmental Enteric dysfunction Jan 2018– Dec 2020 Aug 2017 – March 2020 Core Equipment Grant Equipment

  11. Bench no. A-19 Dr. Farah Qamar Associate Professor Paediatrics & Child Health. The Aga Khan University, Pakistan Salmonella CRO This is a case control study of outbreak investigation of Ceftriaxone resistant Salmonella typhi and assessment of typhoid conjugate vaccine in Hyderabad, Sindh, Pakistan Sep 2017 – Jun 2019 Core Equipment Grant Equipment

  12. Bench no. A-20 Dr. Imran Nisar Assistant Professor Pediatrics & Child Health. The Aga Khan University, Pakistan INDIRECT PCV-10 This study aims to investigate the Indirect effect of PCV10 on nasopharyngeal carriage in children under 5 years of age in a rural community in Pakistan July 2014 – Dec 2018 Core Equipment Grant Equipment

  13. Bench no. A-21 Role of Arboviruses-cause of undifferentiated fever The primary objective of this study is to determine the burden of Arboviruses as a cause of unexplained fever in the Sind province of Pakistan. The study will be covering epidemiology and prevalence of Dengue Virus, Chikunguniya Virus, west Nile Virus and Japanese B Encephalitis Virus. Dr. Erum Khan Professor Pathology & Lab Medicine. The Aga Khan University, Pakistan Mar 2014 – Dec 2019 Core Equipment

  14. Bench no. A-22 Dr. Rumina Hasan Professor Pathology & Lab Medicine. The Aga Khan University, Pakistan • AMR Surveillance • This grant is designed to work towards strengthening lab capacity for antimicrobial testing in three phases; capacity for drug sensitivity testing, investigating AMR in specific community and hospital based organisms and Identifying gaps to support AMR training and research June 2017– Sep 2019 Core Equipment Shared with Clinical Labs

  15. Bench no. A-23 & A-24 Dr. M. Yousuf Assistant Professor Centre for Regenerative Medicine and Stem Cell Research. The Aga Khan University, Pakistan A 3D in vitro study to elucidate the microenvironment of prostate cancer and metastasis. Nov2018 – Aug 2019 Core Equipment CRM Equipment

  16. Bench no. A-25 Dr. Salma Jahan Assistant Professor Centre for Regenerative Medicine and Stem Cell Research. The Aga Khan University, Pakistan Differentiation study of hTRET MSC into hepatocyte-like cells. Nov2018 – Aug 2019 Core Equipment CRM Equipment

  17. Dr. Azhar Hussain. Director CRM Centre for Regenerative Medicine and Stem Cell Research. The Aga Khan University, Pakistan Bench no. A-26 TargettingOxaliplatin resistance breast cancer with small molecular inhibitors of over expressing prosurvival and antiapoptotic proteins. Nov2018 – Aug 2019 Core Equipment CRM Equipment

  18. Bench no. A-27 Dr. Farah Qamar Associate Professor Paediatrics & Child Health. The Aga Khan University, Pakistan Sep 2018– Aug 2020 ABCD sub study Diarrhea etiologies and their impact on the efficacy of azithromycin for treatment of severe diarrhea Core Equipment Grant Equipment

  19. Bench no. A-28 Dr. Rumina Hasan Professor Pathology & Lab Medicine, The Aga Khan University, Pakistan • Bedaquiline MIC on Agar • This is a protocol optimization project where the TB organism is grown in specialized agar medium known as 7H11 and 7H10. The method determines to find out minimal inhibitory concentration at which organisms causing TB can be sensitive. Dec 2015 –Dec 2019 Core Equipment Shared with Clinical Labs

  20. Bench no. A-29 Dr. Syed Adnan Associate Professor Department of Surgery The Aga Khan University, Pakistan Correlation of Molecular Markers expression and overall survival in Pancreatic Adeno Carcinoma Patients. Feb 2019 – Feb 2021 Core Equipment

  21. Bench no. A-30 Dr. Ather Enam Professor Department of Surgery. The Aga Khan University, Pakistan Dr. Syed Adnan Associate Professor Dapartment of Surgery.The Aga Khan University, Pakistan Stem Cell Markers in Glioblastoma March 2018 – March 2020 Gene expression of cancer stem cell markers in Glioblastoma multiforme. June 2018 – June 2020 Core Equipment

  22. Bench no. B-5 Dr. Hammad Hasan Assistant Professor Centre for Regenerative Medicine and Stem Cell Research. The Aga Khan University, Pakistan Generation of human adult erythroid cell line for the sustainable production of red blood cells. Nov 2018 – Aug 2019 Core Equipment CRM Equipment

  23. Bench no. B-6 Dr. El-Nasir Lalani Director CRM Centre for Regenerative Medicine and Stem Cell Research. The Aga Khan University, Pakistan Staining Bench- H & E. Pathology Core. Nov 2018 – Aug 2019 Core Equipment CRM Equipment

  24. Bench no. B-7 & B-8 Dr. Afsar Mian. Assistant Professor Centre for Regenerative Medicine and Stem Cell Research. The Aga Khan University, Pakistan Role of DHT and HER-2 expression in breast cancer Nov 2018 – Aug 2019 Core Equipment CRM Equipment

  25. Bench no. B-9 Dr. Junaid Iqbal. Assistant Professor Pediatrics & Child Health. The Aga Khan University, Pakistan Development of Intestinal Organoids from Environmental Enteropathy Patient’s Gut Jan 2018 – Oct 2019 Core Equipment

  26. Bench no. B-10 Dr. Ali Faisal Saleem Assistant Professor Paediatrics & Child Health. The Aga Khan University, Pakistan • CHAIN PROTOCOL • This is a cohort study, aiming towards evidence based care of acutely ill, undernourished children in limited resource settings – cohort study Oct 2016 – Mar 2019 Core Equipment Grant Equipment

  27. Bench no. B-11 & 12 Dr. S. Asad Ali Associate Professor Pediatrics & Child Health. The Aga Khan University, Pakistan SEEM Pakistan This Study covers the aspect of Environmental enteropathy & malnutrition in Pakistan Nov 2015 – Oct 2019 Core Equipment Grant Equipment

  28. Bench no. B-13 Dr. Fyezah Jehan Assistant Professor Pediatrics & Child Health. The Aga Khan University, Pakistan Impact of lung ultrasound (PLUS) on management of pneumonia in low resource settings. Oct2018– March 2019 Core Equipment Grant Equipment

  29. Bench no. B-15 Dr. Zahra Hasan Professor Pathology & Lab Medicine. The Aga Khan University, Pakistan • From latent tuberculosis to active TB: • It will help understanding the mechanism of disease progression in Diabetes with reference to suppressor of cytokine signaling molecules (SOCS). Apr 2018 – Jan 2020 Grant Equipment

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