1 / 29

The hypothalamo-pituitary axis

The hypothalamo-pituitary axis. petercelec@gmail.com. Hypothalamus. Nervous regulation of the autonomous nervous system – adrenal medulla Production of ADH and oxytocin supraoptical and paraventricular nuclei neurophysin Regulation of hormone production in the pituitary grand.

clover
Download Presentation

The hypothalamo-pituitary axis

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. The hypothalamo-pituitary axis petercelec@gmail.com

  2. Hypothalamus • Nervousregulationoftheautonomousnervoussystem – adrenalmedulla • Productionof ADH and oxytocin • supraoptical and paraventricularnuclei • neurophysin • Regulationofhormoneproduction in thepituitary grand

  3. Hypothalamus • Liberins • CRH (ACTH), TRH (TSH), GHRH (GH), GnRH (LH, FSH), Salsolinol (PRL) • Statins • Somatostatin (GH), Dopamin (PRL)

  4. Overview

  5. GnRH

  6. GHRH

  7. Prolactin

  8. Prolactin functions • Lactation • Immunomodulation? • Behavior? • Water and electrolyte balance? • Metabolism? • Reproduction?

  9. CRH

  10. TRH

  11. ADH - vasopressin

  12. ADH - vasopressin

  13. Oxytocin

  14. Oxytocin

  15. ADH & oxytocin

  16. Pathology

  17. GH • Overproduction of GH • Gigantism • Acromegaly • GH deficiency • Nanism • GH deficiency sy • Somatopause

  18. ADH disorders • Deficiencyof ADH • Diabetes insipidus • Polydipsia, polyuria • Central • Renal • Overproductionof ADH • Syndromeof IAD • Hypoosmolalityofplasma, hyponatriemia, oliguria

  19. Hypopituitarism • General • Selective • Trauma, infection, hemorrhage , tumors... • Inborn errors • Therapy - supplementation

  20. Sheehan's syndrome • Intra-partum infarction of the pituitary gland • mother & child • GH – LH/FSH – TSH • Consequences?

  21. Discussion • Journalinfo, authorinfo? • Aim? • Objects? • Methods? • Main results? • Limitations? • Application? • Conclusions?

More Related