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Cocos Gram positivos. Escarlatina: lengua aframbuesada. Cocos. (microscopio electrónico). Cocos. Microcopía electrónica. Streptococcus. Streptococcus pneumoniae en Gram de expectoración. Cocos. Microscopía electrónica. Cocos Gram positivos en frotis de expectoración.
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Neumococo en frotis de expectoración. Diplos y cadenas cortas.
MICs Oxacillin Susceptible Oxacillin Intermediate Oxacillin Resistant S. aureus <2 g/ml no intermediate MIC >4 g/ml CoNS <0.25 g/ml no intermediate MIC >0.5 g/ml Zone sizes Oxacillin Susceptible Oxacillin Intermediate Oxacillin Resistant S. aureus >13 mm 11-12 mm <10 mm CoNS >18 mm no intermediate zone <17 mm Puntos de corte (breakpoints) de MIC y disco-difusión para oxacilina frente a S. aureus y frente a Staphylococcus coagulasa negativos (CoNS)
How is the mecA gene involved in the mechanism of resistance?Staphylococcal resistance to oxacillin/methicillin occurs when an isolate carries an altered penicillin-binding protein, PBP2a, which is encoded by the mecAgene. The alteration of the penicillin-binding protein does not allow the drug to bind well to the bacterial cell, causing resistance to -lactam antimicrobial agents.