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treatment

Coagulopathy of Liver Failure. treatment. Fresh Frozen Plasma Most effective way to correct hemostasis in patients with liver failure Infusion (5-10mL/kg) sufficient to ensure 10-20% of normal levels of clotting factors but not correction of PT or aPTT. Platelet concentrates

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treatment

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  1. Coagulopathy of Liver Failure treatment

  2. Fresh Frozen Plasma • Most effective way to correct hemostasis in patients with liver failure • Infusion (5-10mL/kg) sufficient to ensure 10-20% of normal levels of clotting factors but not correction of PT or aPTT

  3. Platelet concentrates • Indicated when platelet counts are <10,000 – 20,000/mm3 to control an ongoing bleed or immediately before an invasive procedure if counts are <50,000/mm3

  4. Cryoprecipitate • Indicated only when fibrinogen levels are <100mg/ml • 6 bags for 70-kg patient daily

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