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Cardiometabolic Risk Factors in Iranians with Spinal Cord Injury: An Analysis by Injury-Related Variables

This study explores cardiometabolic risk factors in individuals with spinal cord injury, highlighting the association of injury level with abnormalities in carbohydrate and lipid metabolism that can lead to coronary heart disease. Results reveal high prevalence of diabetes, dyslipidemia, hypertension, and obesity in these patients.

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Cardiometabolic Risk Factors in Iranians with Spinal Cord Injury: An Analysis by Injury-Related Variables

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  1. Cardiometabolic risk factors in Iranians with spinal cord injury: Analysis by injury-related variables Hadis Sabour, MD, PhD; Abbas Norouzi Javidan, PhD; Neda Ranjbarnovin, MD; Mohammad Reza Vafa, PhD, MSPH; Zahra Khazaeipour, MD; Firoozeh Ghaderi, BSc; Fatemah Khanzadeh Mehrabani, BSc; Farzad Shidfar, PhD, MSc

  2. Aim • Perform detailed analysis of level-specific cardiometabolic risk factors in individuals with spinal cord injury (SCI). • Analyze association of injury level on these risk factors. • Relevance • Persons with SCI have high prevalence of abnormalities in carbohydrate and lipid metabolism. • These abnormalities cause adverse coronary heart disease (CHD) in patients with SCI.

  3. Method • Cross-sectional study of 162 patients with SCI, assessing prevalence of: • Diabetes mellitus. • Dyslipidaemia. • Hypertension. • Obesity. • Smoking. • Also diagnosed fasting blood sugar in 27 patients.

  4. Results • Total cholesterol (TC) >200: • 36 patients. • Triglyceride >150: • 56 patients. • Hypertension: • 2.5% of patients. • Body mass index (BMI), TC, and low-density lipoprotein cholesterol (LDL-C): • Significantly higher in patients with paraplegia than in patients with tetraplegia.

  5. Conclusion • Patients with paraplegia may have increased hypertension, higher BMI, and increasing levels of serum LDL-C and TC compared with those with tetraplegia. • Conventional risk factors for CHD should be identified and treated in individuals with SCI.

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