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phoma herbarum allergy

Mouse monoclonal antibody to bacteria cladosporium herbarum race 4.<br><br>https://www.creative-diagnostics.com/Anti-Bacteria-Cladosporium-Herbarum-Race-4-Antibody-53225-144.htm<br>

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phoma herbarum allergy

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  1. Anti-C. herbarum Monoclonal antibody Anti-C. herbarum Monoclonal antibody (DMAB9403) (DMAB9403) This product is for research use only and is not intended for diagnostic use. PRODUCT INFORMATION PRODUCT INFORMATION Product Overview Product Overview Mouse monoclonal antibody to bacteria cladosporium herbarum race 4. Target Target C. herbarum Immunogen Immunogen Cladosporium herbarum race 4 prepared at Plant Sciences, University of Oxford, UK from PBS, cell free surface washings (5 ml) of 14-day-old cultures. Isotype Isotype IgM Source/Host Source/Host Mouse Species Reactivity Species Reactivity C. herbarum Conjugate Conjugate Unconjugated Applications Applications ELISA Size Size 1 ea Storage Storage -20 °C, Avoid freeze / thaw cycles BACKGROUND BACKGROUND Introduction Introduction Cladosporium herbarum is a fungal plant pathogen. Its hosts include Bryum, Buxbaumia, Gyroweissia, Tortula, and Dicranella. The ascomycete Cladosporium herbarum is a prominent fungal inducer of Type I allergy. The only major allergen identified so far is Cla h 8, a NADP- dependent mannitol dehydrogenase (MtDH). MtDH, a cytoplasmic protein of 28.5kDa, belongs to the Short chain Dehydrogenases/Reductases (SDR), acting as a NADP-dependent oxidoreductase. In this study, we found that C. herbarum MtDH can exist as monomers, dimers and tetramers in solution and, correspondingly, forms tetramers and higher oligomers in two crystal structures. The formation of oligomers and higher multimers of MtDH provides a missing link to its allergenic properties. We can also clarify the atypical enzymatic properties of MtDH by two alternative binding modes of the substrate to the active site. Keywords Keywords C. herbarum race 4; Cladosporium herbarum race 4 45-1 Ramsey Road, Shirley, NY 11967, USA Email: info@creative-diagnostics.com Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved

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