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Custom Conjugation

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Custom Conjugation

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  1. Custom Conjugation Normally, an antigen is a large, complex molecule with a molecular weight greater than 10kDa and as such, is able to promote a good immune response and induce high levels of specific antibody. Peptides are very small molecules, typically 1000-2000 Daltons, which even when emulsified in adjuvant are able to elicit only a very poor immune response. Such small molecules are called haptens. As a result, it is necessary to conjugate the peptide to a larger carrier molecul, such as Protein, Oligonucleotide, Enzyme, Metal Chelates, etc.

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