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HYPERTENSION BY: Miss Santoshi naik Assistant professor Yenepoya pharmacy college & research centre. HYPERTENSION Hypertension is defined as systolic blood pressure (SBP) of 140 mmHg or greater & diastolic blood pressure (DBP) of 90 mmHg or greater. TYPES OF HYPERTENSION.
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HYPERTENSION BY: Miss Santoshinaik Assistant professor Yenepoya pharmacy college & research centre
HYPERTENSION Hypertension is defined as systolic blood pressure (SBP) of 140 mmHg or greater & diastolic blood pressure (DBP) of 90 mmHg or greater.
TYPES OF HYPERTENSION ESSENTIAL HYPERTENSION (PRIMARY HYPERTENSION) SECONDARY HYPERTENSION
1) Primary Hypertension • 95% cases of hypertension. • No underlying cause but may occur due to lifestyle changes & genetics. 2) Secondary Hypertension • Remaining 5% cases of hypertension. • Underlying causes: Chronic artery disease, nephrotic syndrome, hyperthyroidism, sleep apnoea, chronic alcohol, oral contraceptives, hyperaldosteronism, Drugs e.g. cocaine, Pre-eclampsia
Signs & Symptoms of Hypertension • Headache • Dyspnoea • Visual changes (retinopathy) • Chest pain • Sensory or motor problems • Palpitations • Anxiety • Nose bleeding
Pathology of Hypertension Vascular changes Remodelling Hypertrophy NORMAL Blood vessel wall Lumen EARLY HYPERTENSION Plaque LATE HYPERTENSION
In normal blood vessels there is no restriction to blood flow. • In case of early hypertension there is plaque formation & thus there is slight decrease in blood flow. • In case of late hypertension there is increased plaque formation and hypertrophy of the vessel wall, which results in narrowing of lumen & thus diminished blood flow. This results in aggravating the hypertension, because of increased pressure exerted by blood on the walls of the vessels.
Risk / Predisposing Factors of Hypertension • Obesity • High alcohol intake • Family history • Diabetes • High sodium intake • Old age • Sleep apnoea (sleep disorder where breathing stops & starts).
Diagnosis of Hypertension • ECG (Electro Cardio Gram) to check heart function • Urine analysis to check renal function • Serology- Plasma renin, plasma aldosterone & thyroid function test (TFT)
Management of Hypertension • Exercise • Reduce salt intake • Reduce intake of alcohol • Cessation of smoking • Maintain proper healthy diet • Antihypertensive medications