Unconstrained Sleep Measuring Device for Breathing Movement 非穿戴式睡眠呼吸運動量測裝置

Unconstrained Sleep Measuring Device for Breathing Movement 非穿戴式睡眠呼吸運動量測裝置 Presenter: Kun-Han Jhan Advisor: Dr. Chun-Ju Hou Date:2013/12/25

Outline • Problems and Rationale • Purpose and Specific Aims • Background and Literatures Review • Materials and Methods • Preliminary Results • References

Problems and Rationale • Insomnia ratio: 19.3 % • Taiwan Society of Sleep Medicine (2013)

Problems and Rationale • Sleep disorders • Arousal and sleep fragmentation • Much movement during sleep • Restless legs syndrome during sleep • Periodic limb movements during sleep • Sleep apnea

Problems and Rationale • Sleep apnea features • Snoring • Fatigue • Sleep deficit • Duration of breathe pause:10s~90s

Problems and Rationale • Technologies for the evaluation of sleep problems • Evaluating the quality of sleep • Sleep diary, questionnaire • Polysomnography (PSG), actigraph • Preventing pressure sore and falling • Air mattress, image monitor, pressure sensing mattress

Problems and Rationale • Disadvantage of current techniques in evaluating the quality of sleep • Subjective evaluation • Need to memorize sleeping status after waking up • Need to wear multiple sensors on body • Limitation of manpower in clinical care • The privacy problem

Purpose and Specific Aims • Design an unconstrained sleep measuring device for breathing movement. • Analog and digital circuits design • System calibration and experimentalverification

Background and Literatures Review • Validation of Unobtrusive Pressure Sensor Array for Central Sleep Apnea Screening Daphne Townsend, Student Member, Raﬁk Goubran, Fellow, Frank Knoefel, and Judith Leech IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT, VOL. 61, NO. 7, JULY 2012

Background and Literatures Review • Identifying body movement

Background and Literatures Review • Pressure Sensor Array v.s PSG

Background and Literatures Review • Detection of Sleep Disordered Breathing with Pressure Bed Sensor Guillermina Guerrero, Juha M. Kortelainen,Elvia Palacios, Anna M. Bianchi,Giulia Tachino, Mirja Tenhunen, Martin O. Méndez,and Mark van Gils 35th Annual International Conference of the IEEE EMBS,Osaka, Japan, 3 - 7 July, 2013

Background and Literatures Review • The eight different Pressure Bed Sensor respiration signals

Materials and Methods • System architecture Analogy and Digital Circuits Computer Analogy Circuit Module Digital Signal Process Pressure Sensor Mattress Digital Circuit Module Display Pressure Signal BluetoothModule

Materials and Methods • System architecture Sensor 1~7 7 –Channel analog signal Constant Voltage Source Bridge circuit AD623 Sensor 8~14 Constant Voltage Source Bridge circuit AD623 Sensor 15~21 Constant Voltage Source Bridge circuit AD623 Pressure Sensor Mattress Multi-channel measurement module Sensor 22~28 Constant Voltage Source Bridge circuit AD623 Sensor 29~35 Constant Voltage Source Bridge circuit AD623 Sensor 36~42 Constant Voltage Source Bridge circuit AD623 Sensor 43~49 Constant Voltage Source Bridge circuit AD623

Materials and Methods • Pressure Sensor • Force sensing resistors (FSR) • Flexible

Materials and Methods • Design of sensor pad • Size: 70cm × 70cm • No. of sensor: 7 × 7 FSRs

Materials and Methods • Bridge circuit • Can detect small resistance changes • Adjust the lower limit of measurement

Materials and Methods • Instrumentation Amplifier • AD623 • Frequency response • 800kHz at gain:1 • CMRR: 90dB

Materials and Methods • Multi-channel measurement module • 7 Multiplexer • 1 Decoder

Materials and Methods • MSP430F5438A • Low Supply Voltage Range • 2.2Vto 3.6V • Ultralow Power Consumption • A/D converter with 12-bit,and 16-channel input • 4USCI • 16K RAM • 256 KB Flash Memory • Shortest cycle instruction execution 125ns • I/O pins:87

Materials and Methods • Bluetooth Mode • BTD43x • Low cost • Low power • Serial Port Profile • HyperTerminal Settings • Transmission distance:100m

Materials and Methods • System Caliration • FSRcalibration • System calibration

Materials and Methods • FSR calibration Different Force input (20 g to 500 g) Pressure sensor Multi-meter (K ohm)

Materials and Methods • Calibration of analog circuit different input resistance Analog circuit (49 channel) Multi-meter (V) Input resistance 150k Ω 7k 3k 2k 1k 0.5k

Preliminary Results • FSR calibration

Preliminary Results • Digital circuit calibration

Preliminary Results • Pressure distribution Aspiratory Aspirated

References • 台灣睡眠醫學學會http://www.tssm.org.tw/ • Daphne Townsend, Student Member, IEEE, Raﬁk Goubran, Fellow, IEEE, Frank Knoefel, and Judith Leech(2012), Validation of Unobtrusive Pressure Sensor Array for Central Sleep Apnea Screening,IEEE • Guillermina Guerrero, Juha M. Kortelainen,Elvia Palacios, Anna M. Bianchi, Member,. IEEE,Giulia Tachino, Mirja Tenhunen, Martin O. Méndez,and Mark van Gils, Member, IEEE (2013) "Detection of Sleep-Disorbered Breathing with Pressure Bed Sensor",IEEE, vol. 35, pp. 1342 - 1345

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Unconstrained Sleep Measuring Device for Breathing Movement 非穿戴式睡眠呼吸運動量測裝置