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This assessment evaluates the current practices for rescreening chlamydia in Region II, aiming to establish a baseline measure of rescreening rates and inform discussions on regional rescreening practices.
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Assessment of Chlamydia Rescreening Practices Kelly Opdyke, MPH Region II IPP Advisory Committee Mtg May 16-17, 2007 Cicatelli Associates Inc.
Region II IPP Strategic Plan 2005-2009 • PRIORITY 2: Incorporate Analysis of Regional Prevalence Monitoring Data for Regional and Local Data-Directed Planning and Quality Assurance. • GOAL: IPP data will direct the most cost effective implementation of screening and treatment funds • OBJECTIVE 2C: By June 30, 2007, evaluate/ assess chlamydia rescreening practices for clients testing positive for chlamydia 3-4 months post treatment.
CDC STD Tx Guidelines • Retest all females approximately 3 months after treatment for chlamydia. • Retest all women treated for chlamydial infection whenever they next seek medical care within the following 3–12 months, regardless of whether the patient believes that her sex partners were treated. • Test-of-Cure (repeat testing within 3-4 weeks, i.e. 21 to 28 days) is not recommended except in pregnant women.
Rationale for Rescreening • High prevalence of chlamydia infection is observed in women treated for chlamydial infection in the preceding several months. • Niccolai et al. (Mar 2007) found that 52% of Ct infections in their study population of 14-19 year old females were recurrent infections • Most posttreatment infections result from reinfection • Repeat infections confer an elevated risk for PID and other complications when compared with the initial infection.
Rescreening Assessment Purpose and Aims • Purpose: To assess current practices for chlamydia rescreening in Region II • Specific Aims: • Develop and pilot methodology for Regional rescreening assessment • Establish a baseline measure of rescreening rates to inform future discussions related to regional rescreening practices • Methods were developed in consultation with Screening Workgroup
Rescreening Assessment Methodology • Eligible clients were females (all ages) testing positive for chlamydia between January 1 and December 31, 2005 • Follow-up period through December 31, 2006 • Data requested from sites currently able to provide electronic data with the following variables: • Client ID (to link initial and f/u tests) • Client age • Date of Initial Positive Ct Test • Date of Follow-Up Ct Test • Result of Follow-Up Ct Test
Rescreening AssessmentOutcome Measures • Elapsed time from initial positive Ct test to next Ct test, by age group • Approx. 3 months (75-99 days) • Approx. 3-12 months (100-365 days) • Repeat Ct positivity by age group
Rescreening AssessmentStudy Sample Undup. Number of Females Testing Positive for Chlamydia from January 1 to December 31, 2005 (N=4568)
Rescreening AssessmentResults Undup. Number of Females Retested for Chlamydia Within 3-12 Months After Initial Positive Test (N=4568)
Rescreening AssessmentResults (cont’d) Repeat Chlamydia Positivity Among Females Retested for Chlamydia 3-12 Months After Initial Positive Test (n=1221)
Rescreening AssessmentSummary • 1,221 (26.7% of) females who tested positive for Ct in CY2005 were rescreened within 3-12 months (75-365 days) per CDC guidelines • 16.7% positivity at follow-up • An addt’l 414 (9.1% of) clients were retested within 22-74 days • 12.1% positivity at follow-up • Overall, 1,635 (35.8% of) clients were retested within 22-365 days • 15.5% positivity at follow-up • Just 1.6% (71) of all clients were retested within less than 21 days • Could be prenatal test-of-cure (data not collected)
Rescreening AssessmentDiscussion • What are project areas currently doing to assess rescreening practices? • What have been the results so far? • How can we expand rescreening assessment to include additional project areas and sites? • How do these data support retesting women for chlamydia?