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Cancer T reatment Options. Today’s Objective:. Identify different options of cancer therapy . Most cancers are treated with a combination of approaches . Treatment:. 1-local therapy: - surgery - radiation 2-systemic treatment: chemotherapy. Hormonal therapy. 3-supportive care.
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Today’s Objective: • Identify different options of cancer therapy. • Most cancers are treated with a combination of approaches
Treatment: • 1-local therapy: • -surgery • -radiation • 2-systemic treatment: • chemotherapy. • Hormonal therapy. • 3-supportive care. • 4-non-conventional therapy.
Surgery: • Surgery was the first modality used successfully in the treatment of cancer. • It is the only curative therapy for many common solid tumors. • successful surgical therapy is often dependent on if the cancer has spread beyond the tumor
Surgery, Cont: • Surgery may be used to slow down the cancer spread in patients for whom cure is not possible. • Has significant role in cancer prevention
Surgery for prevention: • Patients with conditions that predispose them to certain cancers or with genetic traits- family history
Radiation therapy: • Success depend in the difference in the radio sensitivity b/w the tumor and normal tissue. • It involves the administration of x-ray or gamma rays to the tumor site.
Radiation Therapy • Planned and performed by a team of nurses, physicians and a radiation oncologist. • Delivered in small doses- 5 times a week for a total course of 5-8 weeks. • main treatment in Hodgkin’s disease, gynecologic tumors & CNS tumors
Complication of radiation: • Radiation can be toxic to your healthy cells! • Short term symptoms- Fatigue, local skin reactions, GI toxicity • Can cause other tumors and cancers to develop
Chemotherapy: • Chemotherapy is the main treatment available for cancers which have spread beyond main tumor site. • Chemotherapy advances have resulted in cures for several tumors. • Chemotherapy usually require multiple cycles.
Chemotherapeutic agents: • Alkylating agents: • Antimetabolites: • Antitumor antibiotic: • Plant alkaloids: • Hormonal agent: • Immunotherapy:
Chemotherapy Complications: • These CHEMICALS have side effects on normal, healthy tissue . • E.G;, nausea & vomiting and the loss of red blood cells are the most frequently observed side effects.
Criteria used to describe response to treatment are: • Complete response (complete remission) the disappearance of all detectable malignant disease. • Partial response: decrease by more than 50% • Stable disease: no increase in size of any lesion nor the appearance of any new lesions. • Progressive disease: means an increase by at least 25% or the appearance of new lesions.