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Healthier Lives Through Research Partnerships David B. Abrams, Ph.D. Director

Healthier Lives Through Research Partnerships David B. Abrams, Ph.D. Director. Tobacco Use & Cancer in the US. Per Capita Cigarette Consumption. Male lung cancer death rate. Female lung cancer death rate.

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Healthier Lives Through Research Partnerships David B. Abrams, Ph.D. Director

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  1. Healthier Lives ThroughResearch PartnershipsDavid B. Abrams, Ph.D.Director

  2. Tobacco Use & Cancer in the US Per Capita Cigarette Consumption Male lung cancer death rate Female lung cancer death rate *Age-adjusted to 2000 US standard population. Source: Death rates: US Mortality Public Use Tapes, 1960-2002, US Mortality Volumes, 1930-1959, National Center for Health Statistics, Centers for Disease Control and Prevention, 2005. Cigarette consumption: US Department of Agriculture, 1900-2002.

  3. A New Vision • Capitalize on new discoveries and new tools • Informatics • Computer technology • Genetics • Conduct interdisciplinary science • Build partnerships to solve problems whose scope overwhelms single research paradigms “The idea of a sharp distinction between health and disease is a medical artifact for which nature, if consulted, provides no support.” Pickering (1937)

  4. Scope of the Science

  5. Healthy Public Policy Primary & Secondary Prevention / Treatment Primary & Secondary Prevention / Treatment Levels of Causation for Health Levels of Causation Interventions Environmental Influences Social Position Organization & Community Interventions Social & Cultural Processes Primary & Secondary Prevention Psychological Processes Biological & Genetic Factors Adapted from McKinlay, J. B., & Marceau, L. D. (2000). Public health matters. Am J Pub Hlth, 90, 25-33, p. 29.

  6. From Basic Science to Policy Source: Abrams, D.B. (1999). Transdisciplinary paradigms for tobacco prevention research. Nicotine & Tobacco Research, 1, S15-S23. Adapted from: Greenwald & Cullen, National Cancer Institute, 1986.

  7. With a Focus on Population Impact • A large number of people at small risk may give rise to more cases of disease than a small number of people at high risk. • A preventive measure that brings large benefits to the community affords little to each participating individual. • ~ Rose, 1992 Source: Rose, G. (1992). The Strategy of Preventive Medicine. Oxford, England, Oxford University Press.

  8. Exciting New Opportunities for BSSR • Macro-Social Behavior (e.g., migration) • Social & Interpersonal Behavior (e.g., ethnic bias) • Perception, Learning, Emotion & Cognition (e.g., vigilance) • Early Development (e.g., temperament) • Gene-Environment Interactions (e.g., bio-social stress) • Technology, Measures & Methods (e.g., biomarkers) • Cross-cutting research (e.g., health disparities, obesity, early life events) Source: Research Opportunities in the Basic Behavioral and Social Sciences at NIH. Report of the Working Group of the NIH Advisory Committee to the Director December 2, 2004.

  9. OBSSR’s Vision The vision of OBSSR is to mobilize the biomedical, behavioral, and social science research communities as partners to solve the most pressing health challenges faced by our society. Programmatic Directions to Achieve the Vision: • “Next generation” basic science • Interdisciplinary research • Systems-thinking approaches to health • Problem-Based research

  10. “Next Generation” Basic Science OBSSR will support and facilitate the next generation of basic behavioral and social science research informed by breakthroughs in complementary areas such as genetics, informatics, and multilevel analyses.

  11. Systems-thinking Approaches to Health OBSSR will stimulate research that integrates multiple levels of analysis – from cells to behavior to society – required to understand the ways in which individual and contextual factors interact to determine health status. International Network for Social Network Analysiswww.insna.org/INSNA/na_inf.html

  12. Problem-Based Research OBSSR will work with its NIH partners to identify problems in population health where behavioral and social scientists, biomedical researchers, practitioners, and health services decision makers can work together to develop prevention, treatment, and policy interventions and to accelerate their translation and adoption. • A focus on outcomes

  13. Funding Support for an Integrated Model • NIH Roadmap • NIH Neuroscience Blueprint • Office of Portfolio Analysis and Strategic Initiatives (OPASI) • Other agencies • National Science Foundation • Centers for Disease Control and Prevention

  14. Conclusions • Behavior is the bridge between biology and society • The vision of OBSSR is to mobilize the biomedical, behavioral, social science, and population science research communities as partners to solve the most pressing health challenges faced by our society.

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