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Bioinformatics for Vet. Review 1st

Bioinformatics for Vet. Review 1st. Sung Youn Lee, PhD. Student Veterinary collage, Room 320 02 450 3719, 016 293 6059 leevet@paran.com. Growth of GenBank. 1982: 600,000 Bases 2002: 28.5 Billion Bases. Image source: www.ncbi.nlm.nih.gov. What is bioinformatics?.

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Bioinformatics for Vet. Review 1st

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  1. Bioinformatics for Vet. Review 1st Sung Youn Lee, PhD. Student Veterinary collage, Room 320 02 450 3719, 016 293 6059 leevet@paran.com

  2. Growth of GenBank • 1982: 600,000 Bases • 2002: 28.5 Billion Bases Image source: www.ncbi.nlm.nih.gov

  3. What is bioinformatics? • Bio(Biology) - informatics (information science) • The computational branch of molecular biology. • in vivo • in vitro • in silico • Computational biology: development of algorithms and statistical models to analyze biological data • Bioinformatics/Computational Biology will be interchanged

  4. 키워드 삽입

  5. Central Dogma DNA  RNA  PROTEIN Image source: unknown

  6. Image source: www.biotec.or.th/Genome/whatGenome.html

  7. Double Helix • Two complementary DNA strands form a stable DNA double helix • Spring 2003 marked the 50th anniversary of its discovery Image source; www.ebi.ac.uk/microarray/ biology_intro.htm

  8. RNA secondary structure • E. coli Rnase P RNA secondary structure Image source: www.mbio.ncsu.edu/JWB/MB409/lecture/ lecture05/lecture05.htm

  9. Transcription

  10. The Peptide Bond • Dehydration synthesis • Repeating backbone: N–C –C –N–C –C • Convention – start at amino terminus and proceed to carboxy terminus O O

  11. Proteins are chains of amino acids • Polymer– a molecule composed of repeating units

  12. Question & Answer • Adenine vs Adenosine Adenosine

  13. Thank you for your attention ~

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