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The YL9100 S HPLC

The YL9100 S HPLC. All your needs for semi-preparative applications. YL9100S HPLC Overview. Superior Performance Greater Reliability Excellent Usability Serviceability and Easy Maintenance. Superior Performance. YL9100S HPLC – Features 1. Higher performance solvent delivery pump

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The YL9100 S HPLC

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  1. The YL9100S HPLC All your needs for semi-preparative applications

  2. YL9100S HPLC Overview • Superior Performance • Greater Reliability • Excellent Usability • Serviceability and Easy Maintenance

  3. Superior Performance YL9100S HPLC – Features 1 • Higher performance solvent delivery pump - New designed carrier assembly and CAM - Improvement of precision • Better UV/Vis detector with new optic design - For better light intensity and higher sensitivity • New Detector – Photo Diode Array with excellent sensitivity Semi-prep flow cell is available

  4. Greater Reliability YL9100S HPLC – Features 2 • Improvement of System components - New designed main parts of Pump, Detectors and Column compartment with very robust materials • Innovative manufacturing process - Three step quality control and assurance system

  5. Excellent Usability YL9100S HPLC – Features 3 • Intuitive, intelligent and powerful software - Easy control window for instruments of YL9100S HPLC - Harmonization Microsoft’s standards for accessing flies, reviewing data and reports, and other tasks - System Suitability Test with USP, EP and JP - Compliance with 21 CFR Part 11 - Diagnostics and Error detection • Automation Perfectly of Analysis work - Startup, analysis operation, shut down, … , and to report generation

  6. Serviceability and Easy Maintenance YL9100S HPLC – Features 4 • Better long-life components - New designed the carrier, CAM, needle bearing, seals and belt (with polyurethane) for long-life time - New designed the Deuterium and Tungsten lamp guaranteed 2,000 hours - Semi-permanent peltier in the Column Compartment • Easy Maintenance • - Easy replacement and pre-alignment of lamps • - Easy replacement of sample cell assembly • - Diagnostics procedure by software

  7. YL9100S HPLC – Modules List of Modules • Degassing Module • Pump • Column Compartment • UV/Vis Detector • PDA Detector • Refractive Index Detector • Prep Autosampler • Fraction Collector • Chromatography Data System

  8. YL9100S HPLC – Modules -HDVM • YL9101S Vacuum Degasser - No fluctuation, shorten warming up • Number of channel : 2 CHs (option: 4 CHs) • Maximum degassing range: 50ml/min • High capacity of chamber: 62ml per channel • Safety & maintenance : Vacuum Error detection • Wide range of Line Voltage : 100-240VAC, ±10%, Wide range • Line frequency : 50/60Hz, ±5% • Power consumption : 50W YL9101S Vacuum Degasser will be available by June

  9. YL9100S HPLC – Modules -HDVM • Helium Degassing Valve Module • Number of channel : 4 CHs • Degassing type: Helium gas (This module is required a He gas cylinder) • Wide range of Line Voltage : 100-240VAC • Line frequency : 50/60Hz

  10. YL9100S HPLC – Modules -VD • Vacuum Degasser – Stand-alone type • Number of channel : 2 CHs • Maximum degassing range: 50ml/min • Wide range of Line Voltage : 100-240VAC • Line frequency : 50/60Hz • Power consumption : 46W

  11. YL9100S HPLC – Modules – Pump • YL9110S Quaternary Pump • YL9111S Binary Pump • YL9112S Isocratic Pump • New design of mechanical parts of pumps • Compressibility Compensation technology • Semi-automatic Prime/Purge • Built-in Leak sensor • Wide flow range by each check valve with two balls • Ultra robust carrier, bearing, belt, etc • For isolation and purification of preparative HPLC • Flow rate: max. 50ml/min

  12. YL9100S HPLC – Modules – BP • YL9111S Binary Pump (Recommended for Semi-prep) • A New Pump for higher throughput and reproducibility • The best pump for High Pressure Gradient System • Built-in Large capacity static mixer • X2 Parallel dual-plunger • Attractive price compared to QP • Ideal pump for semi-prep application

  13. YL9100S HPLC – Modules – QP/IP • YL9110S Quaternary Pump • Attached 4-way mixing valve to QP • YL9112S Isocratic Pump • Improved Isocratic Pump with parallel dual-plunger • Easy upgraded from IP to QP

  14. YL9100S HPLC – Modules -CC • YL9130S Column Compartment - Powerful temperature control • The best temperature precision: ±0.05°C • Powerful Cooling is the standard: down to 4 °C • Preheating available • Semi-automatic injector/Switching valve: up to 1(option) • Column capacity: 300mm – 2ea • Leak sensor • 40 steps programming • Column OD: up to 28mm

  15. YL9100S HPLC – Modules -UVD • YL9120S UV/Vis Detector - Excellent sensitivity • New designed Optic structure: Seya-Namioka • New Blazed Holographic Concave Grating • Excellent Data acquisition rate: up to 50 Hz • Long-life D2 lamp, 2000 hours guarantee • Advanced band width: 5.5 nm • Excellent Sensitivity: <±0.5 x 10-5 AU at 254nm • Integrated cell and slit assembly • Greater cooling of the lamp’s thermal environment • Optimal cell volume and path length for semi-preparative purpose • Leak sensor

  16. YL9100S HPLC – Modules -UVD • YL9120S UV/Vis Detector • What is the Seya-Namioka monochromator - To attach New Blazed Holographic Concave Grating - Extremely low stray light - Highest light intensity - Reduced astigmatism - Very compact design and size - More serviceability - High performance beam splitter - New designed an integrated cell+slit assembly - Excellent band width, 5.5nm

  17. YL9100S HPLC – Modules -PDA • YL9160S PDA Detector - Highest Sensitivity • Optimum wavelength resolution: 1,024 diodes • Wide range from 190 to 950 nm • Highest Sensitivity <±1.0 x 10-5 AU at 254nm, 2 sec rise time <±2.0 x 10-5 AU at 254nm, 1 sec rise time • Fast data acquisition: 50 Hz • Greatest drift level <2.0 x 10-4 AU/h at 254nm, Baseline correction <1.0 x 10-3 AU/h at 254nm

  18. YL9100S HPLC – Modules -RID • YL9170S RID - For universal detection • RI Range : 1.00 ~ 1.75 RIU • Noise : < ±1.0 x 10-7 RIU • Linear dynamic range : 0-20000 μRIU • Flow rate range : 1 ~ 50.0 ml/min • Cell pressure : 6 kg/cm2(84 psi)

  19. YL9100S HPLC – Modules -AS • YL9150 Autosampler – Prep Autosampler - Fully automated work • Sample capacity: 24 vials(10ml for prep) • Sample loop: 10ml • Injection: partial loop • RSD ≤ 1.0% for partial loopfill. • Carry-over < 0.1% • Option: Built-in Peltier cooling (4oC ~ ambient –3oC)

  20. YL9100S HPLC – Modules -FC • Fraction Collector – FC204/203B A stand-alone operation using time, drop or peak based collection • Collect fractions by time, drop or peak with ease; manual collection is also available • Simply set the time or number of drops, press START and walk away • Drop counting: Up to 9,999 drops per fraction Maximum rate: 20 drops/sec • HELP, YES, NO, 0-9 numeric hard keys/four soft keys • 2-line, 24-character display on backlit LCD

  21. 2 Post-run Automatically displays, prints, exports and starts other programs YL9100S HPLC – Modules -CDS • YL-Clarity CDS - Intelligent and Powerful Chromatography Data Station 1 Measuring Four Instruments up to 12 detectors.

  22. 6 7 3 4 5 8 User accounts Sets up access rights and passwords Networked Solution Clarity files can be accessed from networked computers using Clarity Offline software. Audit trail Records selected events and operations into a special file. Column performance Method validation By USP, EP and JP Electronic signature Each chromatogram can be signed electronically. Great Compatibility Window XP/2000. Window Me/98, and Window Vista (32bit) is available YL9100S HPLC – Modules -CDS

  23. YL9100S HPLC – Modules -CDS • YL-Clarity CDS • Perfectly compliance with 21CFR Part 11 • GPC option available • System Suitability Test option available(Method validation) • PDA module option available: 3-D data analysis • Software Validation option available: Software OQ S/W validation kit

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