1 / 4

Fig. S1

a. b. 2.5. 7. 6. 2.0. 5. 1.5. 4. c ell mortality ratio (%). r elative cell number. 3. 1.0. 2. 0 .5. 1. 0. 0. CN 0.1 0.5 1 5 10 20 30. Sal ( m M ). CN 0.1 0.5 1 5 10 20 30. Sal ( m M ). c. 8. **. 6. Alizarin red S staining

darena
Download Presentation

Fig. S1

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. a b 2.5 7 6 2.0 5 1.5 4 cell mortality ratio (%) relative cell number 3 1.0 2 0.5 1 0 0 CN 0.1 0.5 1 5 10 20 30 Sal (mM) CN 0.1 0.5 1 5 10 20 30 Sal (mM) c 8 ** 6 Alizarin red S staining per total area (%) ** 4 2 ** ** 0 control 0.1 0.5 1 5 10 20 mM Salubrinal Fig. S1

  2. a control Sal 1 2 4 8 24 1 2 4 8 24 h p-eIF2a Sal 8 h (clone 14) eIF2a ATF4 b-actin b Relative mRNA abundance OCN 2.0 ATF4 2.0 ** ** ** 1.5 * ** 1.5 ** 1.0 1.0 0.5 0.5 0 CN Sal5 Sal10 Sal20 0 CN Sal5 Sal10 Sal20 Fig. S2

  3. 4 * a b ** 3 cell mortality ratio (%) 2 2.5 1 2.0 0 1.5 CN 5 10 20 relative cell number Gu (mM) 1.0 0.5 6.0 OCN ** 0 c CN 5 10 20 5.0 Gu control Gu (mM) 4.0 Relative mRNA abundance 2 4 8 24 2 4 8 24 h 3.0 p-eIF2a 2.0 * 1.0 eIF2a 0 CN 5 10 20 Gu (mM) ATF4 b-actin d Fig. S3

  4. a 7 b 6 5 cell mortality ratio (%) 4 3 2 1 0 CN Gu Sal RANKL c CN Sal Gu RANKL NFATc1 2.0 b-actin 1.5 relative cell number d 1.0 0.5 0 Relative mRNA abundance Gu Sal CN RANKL NFATc1 TRAP 10 300 200 5 100 0 0 CN Sal RANKL Gu CN Sal RANKL Gu Fig. S4

More Related