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Supplementary Fig. 1 Local regression nonparametric smoothing plot showing the calibration of a base model (age, digital rectal examination findings, number of previous biopsies) and PSA or PCA3- based models

darius-langley
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345_2014_1251_MOESM6_ESM

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  1. Supplementary Fig. 1 Local regression nonparametric smoothing plot showing the calibration of a base model (age, digital rectal examination findings, number of previous biopsies) and PSA or PCA3-based models Perfect predictions correspond to the 45° line. Points estimated below this line correspond to model overprediction, whereas points situated above it correspond to model underprediction. A nonparametric smoothed curve indicates the relationship between predicted probability and observed frequency of PCa at prostate biopsy. PCA3: prostate cancer gene 3; PCA3D: PCA3 density; PSA: prostate-specific antigen; PSAD: PSA density.

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