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Normal Microbial Flora

Medical Microbiology 507. Normal Microbial Flora. Eric Stanbridge PhD. 2007. September 11th Lecture. Tel 824-7042 ejstanbr@uci.edu. Sites of normal microbial colonization. TABLE 7-2. Microorganisms Found on the Skin. Microorganism. Range of Incidence (Per Cent). STAPHYLOCOCCUS.

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Normal Microbial Flora

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  1. Medical Microbiology 507 Normal Microbial Flora Eric Stanbridge PhD 2007 September 11th Lecture Tel 824-7042 ejstanbr@uci.edu

  2. Sites of normal microbial colonization

  3. TABLE 7-2. Microorganisms Found on the Skin Microorganism Range of Incidence (Per Cent)

  4. STAPHYLOCOCCUS

  5. STREPTOCOCCUS

  6. Mixed Flora, including YEAST (Candida)

  7. TABLE 7-3. Microorganisms Found in the Nose and Nasopharynx Microorganism Range of Incidence (Per Cent)

  8. Neisseria meningitidis

  9. HEMOPHILUS

  10. COLIFORMS (Escherichia coli)

  11. TABLE 7-4. Microorganisms Found in the Oropharynx Microorganism Range of Incidence (Per Cent)

  12. TABLE 7-5. Microorganisms Found in the Mouth (Saliva-Tooth Surfaces) Microorganism Range of Incidence (Per Cent) Viridans Group

  13. ACTINOMYCES Gillies & Dodds, Bacteriology Illustrated, R.R. Gillies, 5th Edtion, p125

  14. Treponema

  15. TABLE 7-6Microorganisms Found in the Stomach and Small Intestine Microorganism

  16. H. pylori survives in the submucosal layer

  17. Mixed Flora- Fecal Material

  18. Mixed Flora- Abscess

  19. TABLE 7-9. Microorganisms Found in the Genitourinary Tract Microorganism Range of Incidence (Per Cent) Kidneysand urinary bladder normally sterile, Female and male urethra usually sterile except for short anterior segment Vagina and Uterine Cervix

  20. Dynamics of Lifetime VAGINAL COLONIZATION Birth STERILE 24 hours Mixed Flora: Several weeks Mixed Flora: Puberty  Mixed Flora: Menopause  Mixed Flora persists micrococci enterococci diphtheroids lactobacilli (DÖderlein’s bacillus) Acidic pH Maternal glycogen deposited No Doderlein’s bacillus micrococci - plus non hemolytic streptococci coliforms (E. coli) diphtheroids Glycogen decreased Alkaline pH Includes DÖderlein’s bacillus + yeast + bacteroides (anaerobes) Glycogen redeposited Acidic pH No DÖderlein’s bacillus Glycogen decreased Alkaline pH

  21. Lactobacillus species

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